C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000276893 UHRF2-003 ENSG00000147854 9606 + 9:6413323-6507054 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000276893
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000276893 2.964±0.00 3.229±0.00 1.746±0.00 1.804±0.90 3.079±0.46 5.264±4.02 1.299±1.01 5.637±0.00 2.190±0.95 4.059±1.40 2.568±1.98 4.670±1.10 3.829±0.98 7.449±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001D5 CIL_0001D5_0001 CGP 9:6328375-6507054
CIL_0001D8 CIL_0001D8_0001 CGP 9:6413151-6645650

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005720 ISS nuclear heterochromatin
GO:0006511 IDA ubiquitin-dependent protein catabolic process
GO:0007049 IEA cell cycle
GO:0008270 IEA zinc ion binding
GO:0008283 IEP cell proliferation
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0030154 IEP cell differentiation
GO:0042393 ISS:IEA histone binding
GO:0051726 TAS regulation of cell cycle
GO:0051865 IDA protein autoubiquitination
GO:0071158 IDA positive regulation of cell cycle arrest

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000025739 Uhrf2-001 protein_coding Mus_musculus 0 3618
ENSMUST00000137368 Uhrf2-002 retained_intron Mus_musculus 0 1871
ENSMUST00000123773 Uhrf2-005 retained_intron Mus_musculus 0 1048
ENSMUST00000134518 Uhrf2-003 retained_intron Mus_musculus 0 841
ENSMUST00000112552 Uhrf2-004 protein_coding Mus_musculus 0 627
ENSMUST00000127244 Uhrf2-006 retained_intron Mus_musculus 0 488
ENSMUST00000129420 Uhrf2-007 retained_intron Mus_musculus 0 316
ENSMUST00000150532 Uhrf2-008 retained_intron Mus_musculus 0 305

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