C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: crumbs family member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148204 CRB2 9606 + 9:123356170-123380324 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000359999 CRB2-003 123356170-123374099 protein_coding
  ENST00000373631 CRB2-001 123356260-123378753 protein_coding
  ENST00000460253 CRB2-002 123368779-123380324 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyENST00000373631
Transcript ID Brain Kidney
ENST00000373631 3.680±2.84 3.394±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006WP CIL_0006WP_0001 CGP 9:123356170-123930152

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001707 ISS mesoderm formation
GO:0001756 ISS somitogenesis
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0010718 ISS positive regulation of epithelial to mesenchymal transition
GO:0010951 IMP negative regulation of endopeptidase activity
GO:0014028 ISS notochord formation
GO:0016021 IEA integral component of membrane
GO:0019828 IMP aspartic-type endopeptidase inhibitor activity
GO:0019899 IMP enzyme binding
GO:0030513 ISS positive regulation of BMP signaling pathway
GO:0043234 IDA protein complex
GO:0045121 IC membrane raft
GO:0045199 ISS maintenance of epithelial cell apical/basal polarity
GO:0070062 IDA extracellular vesicular exosome
GO:0072358 ISS cardiovascular system development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000035403 Crb2 crumbs homolog 2 (Drosophila) protein_coding Mus_musculus

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