Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	crumbs homolog 2 (Drosophila)
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000035403	Crb2	10090	+	2:37776249-37799103	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000050372		Crb2-001	37776249-37799103	protein_coding
	ENSMUST00000137693		Crb2-003	37795169-37796616	processed_transcript
	ENSMUST00000147600		Crb2-002	37791171-37793523	processed_transcript
Mus musculus EnsemblGRCm38 Genome Exciting message Genes Gene structures from Ensembl Connecting Transcripts Structures from Ensembl Connecting Powered by Dalliance 0.11.11

Expression Patterns

Transcript ID	Adipose	Bladder	Brain	Colon	Kidney	Lung	Ovary	Placenta
ENSMUST00000050372	1.236±0.10	1.808±0.21	4.617±1.23	0.505±0.03	1.391±0.12	0.847±0.08	1.925±0.56	1.932±0.30

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0006WP	CIL_0006WP_0002	CGP	2:37776249-38287390

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0001707	IMP	mesoderm formation
GO:0001756	IMP	somitogenesis
GO:0005509	IEA	calcium ion binding
GO:0010718	IMP	positive regulation of epithelial to mesenchymal transition
GO:0010951	IEA	negative regulation of endopeptidase activity
GO:0014028	IMP	notochord formation
GO:0016021	IEA	integral component of membrane
GO:0019828	IEA	aspartic-type endopeptidase inhibitor activity
GO:0019899	IEA	enzyme binding
GO:0030513	IMP	positive regulation of BMP signaling pathway
GO:0043234	IEA	protein complex
GO:0045199	IMP	maintenance of epithelial cell apical/basal polarity
GO:0050896	IEA	response to stimulus
GO:0070062	IEA	extracellular vesicular exosome
GO:0072358	IMP	cardiovascular system development

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSG00000148204	CRB2	crumbs family member 2	protein_coding	Homo_sapiens

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