C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methionine sulfoxide reductase B2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148450 MSRB2 9606 + 10:23095506-23122013 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376510 MSRB2-001 23095506-23122013 protein_coding
  ENST00000468633 MSRB2-003 23119144-23120893 processed_transcript
  ENST00000472663 MSRB2-002 23104144-23120954 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376510ENST00000468633ENST00000472663
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376510 2.693±0.00 2.621±0.00 0.650±0.00 2.056±0.68 3.692±2.81 3.411±2.11 6.207±4.57 2.390±1.15 2.178±0.52 2.480±1.71 2.408±0.41 4.526±3.51 5.051±1.82 1.512±0.73
ENST00000468633 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.233±0.00 8.244±0.00 N/A N/A N/A
ENST00000472663 6.984±0.00 10.432±0.00 N/A 9.962±7.79 31.292±0.00 24.535±0.00 53.651±0.00 14.262±11.95 31.399±0.00 21.025±0.00 16.935±0.00 15.401±4.36 18.578±5.74 8.211±5.81

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088N CIL_00088N_0001 VISTA 10:22901909-23502579
CIL_0002CX CIL_0002CX_0001 CGP 10:22928024-23122013
CIL_0002D0 CIL_0002D0_0001 CGP 10:23095506-23194252

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003779 ISS actin binding
GO:0005739 ISS mitochondrion
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006979 IEA response to oxidative stress
GO:0008270 ISS zinc ion binding
GO:0030041 ISS actin filament polymerization
GO:0030091 ISS protein repair
GO:0033743 ISS:IEA peptide-methionine (R)-S-oxide reductase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018459 msrb2 methionine sulfoxide reductase B2 protein_coding Danio_rerio
ENSMUSG00000023094 Msrb2 methionine sulfoxide reductase B2 protein_coding Mus_musculus

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