C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000149257 SERPINH1 9606 + 11:75562056-75572783 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358171 SERPINH1-004 75562086-75572783 protein_coding
  ENST00000524558 SERPINH1-006 75562370-75572782 protein_coding
  ENST00000525492 SERPINH1-013 75562253-75566918 protein_coding
  ENST00000525611 SERPINH1-016 75562864-75568960 protein_coding
  ENST00000525876 SERPINH1-009 75567782-75572782 protein_coding
  ENST00000526242 SERPINH1-010 75562137-75566681 protein_coding
  ENST00000526397 SERPINH1-011 75562243-75568966 protein_coding
  ENST00000526638 SERPINH1-019 75571914-75572783 nonsense_mediated_decay
  ENST00000528760 SERPINH1-017 75563422-75566959 protein_coding
  ENST00000528990 SERPINH1-014 75562827-75566844 protein_coding
  ENST00000529643 SERPINH1-012 75562253-75566849 protein_coding
  ENST00000530284 SERPINH1-003 75562253-75569430 protein_coding
  ENST00000532356 SERPINH1-018 75562346-75569104 protein_coding
  ENST00000533449 SERPINH1-015 75562833-75566801 protein_coding
  ENST00000533603 SERPINH1-001 75562056-75572783 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358171ENST00000524558ENST00000525876ENST00000526638ENST00000530284ENST00000533603
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358171 72.678±0.00 80.269±0.00 1.268±0.00 2.195±1.35 56.255±39.77 80.514±77.01 11.145±9.46 41.629±39.53 8.054±0.17 271.869±0.00 6.292±3.11 129.351±95.42 254.932±69.80 53.243±33.88
ENST00000524558 N/A N/A 0.749±0.00 0.096±0.00 N/A 1.469±0.00 N/A N/A 1.359±0.00 4.133±0.00 N/A N/A N/A N/A
ENST00000525876 N/A N/A N/A 0.112±0.00 3.691±0.00 0.817±0.00 0.579±0.00 N/A 1.391±0.00 4.055±0.00 N/A N/A N/A N/A
ENST00000526638 N/A N/A N/A N/A N/A N/A N/A N/A 3.963±0.00 N/A 2.929±0.44 N/A N/A N/A
ENST00000530284 N/A N/A N/A N/A N/A N/A 1.450±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000533603 N/A N/A N/A 3.680±0.00 N/A N/A N/A N/A 1.913±0.00 N/A 0.768±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NG CIL_0008NG_0001 VISTA 11:75253021-75855707
CIL_0001SV CIL_0001SV_0002 CGP 11:75434640-75572783

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003433 IEA chondrocyte development involved in endochondral bone morphogenesis
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005518 NAS collagen binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005783 NAS endoplasmic reticulum
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005793 IDA endoplasmic reticulum-Golgi intermediate compartment
GO:0006986 TAS response to unfolded protein
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0030198 TAS extracellular matrix organization
GO:0030199 IEA collagen fibril organization
GO:0032964 IEA collagen biosynthetic process
GO:0044822 IDA poly(A) RNA binding
GO:0051082 IEA unfolded protein binding
GO:0051604 IEA protein maturation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019949 serpinh1b serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b protein_coding Danio_rerio
ENSDARG00000075954 serpinh1a serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a protein_coding Danio_rerio
ENSMUSG00000070436 Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 protein_coding Mus_musculus

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