C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mohawk homeobox
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000150051 MKX 9606 - 10:27672875-27746060 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375790 MKX-001 27672875-27746060 protein_coding
  ENST00000419761 MKX-201 27672875-27745849 protein_coding
  ENST00000460919 MKX-002 27718563-27743545 protein_coding
  ENST00000561227 MKX-003 27743242-27745594 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000375790ENST00000419761ENST00000460919ENST00000561227
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000375790 0.206±0.00 N/A 0.531±0.11 N/A 0.176±0.00 N/A N/A N/A N/A N/A 0.991±0.00 N/A
ENST00000419761 0.165±0.00 0.350±0.00 1.691±0.00 0.064±0.00 0.813±0.00 0.020±0.00 0.077±0.06 0.085±0.00 0.755±0.00 0.040±0.00 2.749±0.00 0.009±0.00
ENST00000460919 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.068±0.00
ENST00000561227 N/A N/A N/A N/A N/A N/A N/A N/A 1.037±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00077Z CIL_00077Z_0002 CGP 10:27504174-27746060
CIL_00077Y CIL_00077Y_0002 CGP 10:27672875-27999048

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085 IEA RNA polymerase II transcription factor binding
GO:0002932 IEA tendon sheath development
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007517 ISS muscle organ development
GO:0010468 IEA regulation of gene expression
GO:0010628 IEA positive regulation of gene expression
GO:0030199 IEA collagen fibril organization
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0035990 IEA tendon cell differentiation
GO:0035992 IEA tendon formation
GO:0043565 IEA sequence-specific DNA binding
GO:0045662 IEA negative regulation of myoblast differentiation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075026 mkxb mohawk homeobox b protein_coding Danio_rerio
ENSDARG00000075450 mkxa mohawk homeobox a protein_coding Danio_rerio
ENSMUSG00000061013 Mkx mohawk homeobox protein_coding Mus_musculus

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