C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gamma-aminobutyric acid (GABA) A receptor, alpha 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000151834 GABRA2 9606 - 4:46248427-46475230 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356504 GABRA2-002 46249567-46389379 protein_coding
  ENST00000381620 GABRA2-001 46249343-46389928 protein_coding
  ENST00000503806 GABRA2-008 46312517-46389363 protein_coding
  ENST00000506961 GABRA2-007 46312560-46389382 protein_coding
  ENST00000507069 GABRA2-013 46250289-46388713 protein_coding
  ENST00000507460 GABRA2-003 46363715-46389550 protein_coding
  ENST00000509716 GABRA2-009 46386074-46388713 processed_transcript
  ENST00000510233 GABRA2-010 46250289-46388713 nonsense_mediated_decay
  ENST00000510861 GABRA2-005 46248427-46475230 protein_coding
  ENST00000513005 GABRA2-014 46250289-46388713 nonsense_mediated_decay
  ENST00000514090 GABRA2-011 46248444-46389381 protein_coding
  ENST00000514193 GABRA2-006 46305693-46389788 nonsense_mediated_decay
  ENST00000514236 GABRA2-012 46302507-46305577 nonsense_mediated_decay
  ENST00000515082 GABRA2-004 46260772-46390404 protein_coding
  ENST00000540012 GABRA2-201 46249571-46390039 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381620ENST00000506961ENST00000507069ENST00000507460ENST00000510233ENST00000513005ENST00000514090ENST00000515082ENST00000540012
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381620 0.228±0.00 N/A N/A 0.157±0.00 0.039±0.00 N/A N/A N/A N/A N/A 0.055±0.00 0.233±0.00
ENST00000506961 N/A N/A N/A N/A N/A N/A 0.057±0.00 N/A N/A 0.168±0.05 N/A N/A
ENST00000507069 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.054±0.00 0.040±0.00 N/A
ENST00000507460 N/A 3.744±0.00 0.224±0.00 0.373±0.00 0.010±0.00 0.415±0.00 N/A 0.022±0.00 N/A 0.021±0.01 0.022±0.01 N/A
ENST00000510233 N/A N/A N/A N/A 0.029±0.00 N/A N/A N/A N/A 0.061±0.00 0.049±0.00 N/A
ENST00000513005 N/A N/A N/A 0.646±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000514090 0.244±0.00 4.154±0.00 N/A N/A N/A 0.645±0.00 N/A 0.023±0.00 N/A 0.029±0.00 0.020±0.01 N/A
ENST00000515082 N/A N/A 0.149±0.00 N/A 0.048±0.00 N/A N/A 0.031±0.00 0.018±0.00 0.018±0.00 N/A N/A
ENST00000540012 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.051±0.00 0.029±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002YX CIL_0002YX_0001 CGP 4:46035769-46475230
CIL_0002YU CIL_0002YU_0001 CGP 4:46248427-46909235

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001505 IMP regulation of neurotransmitter levels
GO:0004890 IEA GABA-A receptor activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005254 IEA chloride channel activity
GO:0005886 TAS plasma membrane
GO:0006810 IEA transport
GO:0006811 IEA ion transport
GO:0006821 IEA chloride transport
GO:0006836 IMP neurotransmitter transport
GO:0007165 IEA signal transduction
GO:0007214 IMP gamma-aminobutyric acid signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008503 IMP benzodiazepine receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0030285 IDA integral component of synaptic vesicle membrane
GO:0030424 IEA axon
GO:0034220 IEA:TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0055085 TAS transmembrane transport
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034011 CABZ01072856.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000070005 GABRA2 (2 of 4) gamma-aminobutyric acid (GABA) A receptor, alpha 2 protein_coding Danio_rerio
ENSMUSG00000000560 Gabra2 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2 protein_coding Mus_musculus

Loading