C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, AMPA 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152578 GRIA4 9606 + 11:105609994-105982092 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282499 GRIA4-201 105610073-105982092 protein_coding
  ENST00000393125 GRIA4-001 105610029-105913110 protein_coding
  ENST00000393127 GRIA4-202 105610073-105982092 protein_coding
  ENST00000428631 GRIA4-004 105610724-105913110 protein_coding
  ENST00000525032 GRIA4-002 105610672-105862649 retained_intron
  ENST00000525187 GRIA4-006 105610998-105979739 protein_coding
  ENST00000525921 GRIA4-011 105610266-105612434 protein_coding
  ENST00000525942 GRIA4-007 105933808-105974430 nonsense_mediated_decay
  ENST00000527177 GRIA4-009 105609994-105612434 protein_coding
  ENST00000527669 GRIA4-003 105610121-105614436 protein_coding
  ENST00000527687 GRIA4-012 105842783-105903983 processed_transcript
  ENST00000530497 GRIA4-005 105610998-105982089 protein_coding
  ENST00000531011 GRIA4-013 105610907-105797913 protein_coding
  ENST00000531986 GRIA4-010 105610062-105612434 protein_coding
  ENST00000533094 GRIA4-008 105933942-105980261 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000282499ENST00000393125ENST00000393127ENST00000428631ENST00000525032ENST00000525187ENST00000527177ENST00000527669ENST00000527687ENST00000530497ENST00000533094
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000282499 N/A N/A N/A N/A N/A N/A 0.033±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000393125 N/A 0.056±0.00 N/A 5.532±0.00 0.155±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000393127 N/A N/A N/A 4.619±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000428631 N/A N/A N/A 10.287±5.76 0.098±0.00 0.054±0.00 N/A N/A N/A N/A N/A N/A 0.037±0.01 N/A
ENST00000525032 N/A N/A N/A 17.917±0.00 0.485±0.00 N/A 0.062±0.00 N/A N/A 0.039±0.00 N/A N/A N/A N/A
ENST00000525187 N/A N/A N/A N/A N/A 0.334±0.00 N/A N/A 0.114±0.00 N/A N/A N/A N/A N/A
ENST00000527177 N/A N/A 0.418±0.00 N/A N/A N/A N/A 0.193±0.00 N/A N/A N/A N/A N/A N/A
ENST00000527669 N/A 0.059±0.00 N/A N/A N/A N/A 0.053±0.00 N/A N/A N/A N/A 0.025±0.02 0.066±0.06 N/A
ENST00000527687 N/A N/A N/A N/A N/A 1.228±0.00 N/A N/A N/A N/A N/A 0.037±0.00 N/A N/A
ENST00000530497 N/A 0.142±0.00 N/A 3.475±0.00 0.237±0.03 0.202±0.00 N/A 0.016±0.00 N/A N/A 0.002±0.00 0.007±0.00 0.085±0.05 N/A
ENST00000533094 0.013±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.108±0.00 N/A 0.024±0.00 0.041±0.00 0.158±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004970 ISS:IEA ionotropic glutamate receptor activity
GO:0004971 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006810 TAS transport
GO:0007215 TAS glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0030666 TAS endocytic vesicle membrane
GO:0031982 IDA vesicle
GO:0032281 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0045202 IEA synapse
GO:0045211 IBA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037496 gria4a glutamate receptor, ionotropic, AMPA 4a protein_coding Danio_rerio
ENSDARG00000059368 gria4b glutamate receptor, ionotropic, AMPA 4b protein_coding Danio_rerio
ENSMUSG00000025892 Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) protein_coding Mus_musculus

Loading