C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, AMPA4 (alpha 4)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025892 Gria4 10090 - 9:4417899-4796234 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027020 Gria4-201 4417899-4796234 protein_coding
  ENSMUST00000063508 Gria4-202 4417899-4796234 protein_coding
  ENSMUST00000163309 Gria4-203 4478263-4796234 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027020ENSMUST00000063508ENSMUST00000163309
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027020 1.100±1.09 0.137±0.05 N/A 4.615±2.36 0.214±0.22 0.340±0.08 0.018±0.01 0.280±0.13 0.020±0.01 0.041±0.04 0.003±0.00 0.101±0.06 0.008±0.00 0.194±0.11
ENSMUST00000063508 0.694±0.91 0.104±0.09 1.961±0.08 3.738±1.85 0.155±0.17 0.169±0.00 0.014±0.01 0.595±0.21 0.027±0.03 0.011±0.00 0.015±0.01 0.054±0.04 0.090±0.07 0.357±0.16
ENSMUST00000163309 0.800±0.65 0.316±0.22 N/A 4.686±0.68 0.090±0.04 0.284±0.11 0.007±0.00 0.280±0.10 0.036±0.01 N/A N/A 0.287±0.16 0.042±0.02 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YT CIL_0000YT_0002 CGP 9:4383535-4796234

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004970 ISS ionotropic glutamate receptor activity
GO:0004971 IBA alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0031982 IEA vesicle
GO:0032281 IDA alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0032983 ISS kainate selective glutamate receptor complex
GO:0034220 IBA ion transmembrane transport
GO:0035235 IBA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0045202 IDA synapse
GO:0045211 IBA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037496 gria4a glutamate receptor, ionotropic, AMPA 4a protein_coding Danio_rerio
ENSDARG00000059368 gria4b glutamate receptor, ionotropic, AMPA 4b protein_coding Danio_rerio
ENSG00000152578 GRIA4 glutamate receptor, ionotropic, AMPA 4 protein_coding Homo_sapiens

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