C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, K
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152894 PTPRK 9606 - 6:127968779-128520674 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368202 PTPRK-012 128518928-128520570 processed_transcript
  ENST00000368205 PTPRK-006 128184432-128241299 processed_transcript
  ENST00000368207 PTPRK-018 127970113-128520583 protein_coding
  ENST00000368210 PTPRK-004 127969837-128520616 protein_coding
  ENST00000368213 PTPRK-019 127968977-128520583 protein_coding
  ENST00000368215 PTPRK-005 127969896-128520358 protein_coding
  ENST00000368226 PTPRK-003 127968779-128520674 protein_coding
  ENST00000392449 PTPRK-008 128321403-128520565 nonsense_mediated_decay
  ENST00000415046 PTPRK-009 127985821-128064763 protein_coding
  ENST00000415055 PTPRK-007 127990860-128008077 protein_coding
  ENST00000429595 PTPRK-002 128235380-128322173 processed_transcript
  ENST00000434424 PTPRK-013 128062066-128067677 processed_transcript
  ENST00000490332 PTPRK-001 128184432-128322181 protein_coding
  ENST00000495748 PTPRK-010 128219070-128491857 processed_transcript
  ENST00000498284 PTPRK-011 128184573-128232151 processed_transcript
  ENST00000524481 PTPRK-016 127999987-128520599 processed_transcript
  ENST00000524534 PTPRK-014 128063436-128520515 processed_transcript
  ENST00000525459 PTPRK-017 128321041-128520587 protein_coding
  ENST00000531050 PTPRK-015 127999987-128397617 nonsense_mediated_decay
  ENST00000531466 PTPRK-023 128004977-128009172 retained_intron
  ENST00000532331 PTPRK-020 127968977-128520476 protein_coding
  ENST00000532751 PTPRK-022 128322251-128520599 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368207ENST00000368210ENST00000368213ENST00000368215ENST00000368226ENST00000392449ENST00000495748ENST00000524534
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368207 N/A N/A N/A 5.867±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000368210 N/A N/A 1.362±0.00 3.444±0.09 5.180±0.00 N/A 1.307±0.00 6.371±0.00 N/A N/A 0.646±0.00 N/A N/A N/A
ENST00000368213 N/A N/A N/A N/A N/A 2.801±0.00 0.893±0.00 N/A N/A N/A 0.409±0.00 N/A N/A 0.172±0.00
ENST00000368215 N/A N/A 2.994±0.00 N/A N/A 6.096±0.00 1.159±0.00 2.690±0.00 1.670±0.00 2.359±0.00 0.458±0.00 19.410±7.09 6.051±0.00 0.591±0.00
ENST00000368226 6.291±0.00 2.984±0.00 1.535±0.00 4.542±0.07 3.570±0.76 4.363±0.77 3.590±0.00 5.262±0.77 2.979±1.37 4.799±2.63 0.941±0.00 8.498±0.50 6.303±1.35 3.081±0.00
ENST00000392449 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.970±0.00
ENST00000495748 N/A N/A 8.605±0.00 N/A N/A N/A 8.579±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000524534 N/A N/A N/A N/A N/A N/A N/A N/A 6.164±0.00 N/A 0.896±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001EN CIL_0001EN_0002 CGP 6:127708072-128520674

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001750 IEA photoreceptor outer segment
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005001 NAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IEA protein binding
GO:0005887 NAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006470 IEA protein dephosphorylation
GO:0007155 IMP cell adhesion
GO:0007165 IDA signal transduction
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0008013 IPI beta-catenin binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0010839 IDA negative regulation of keratinocyte proliferation
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016477 IMP cell migration
GO:0016791 IEA phosphatase activity
GO:0019901 IPI protein kinase binding
GO:0030336 IDA negative regulation of cell migration
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0031256 IDA leading edge membrane
GO:0034394 IDA protein localization to cell surface
GO:0034614 IDA cellular response to reactive oxygen species
GO:0034644 IDA cellular response to UV
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0043025 IEA neuronal cell body
GO:0045295 IPI gamma-catenin binding
GO:0045786 IDA negative regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0048041 IMP focal adhesion assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063416 ptprk protein tyrosine phosphatase, receptor type, K protein_coding Danio_rerio
ENSMUSG00000019889 Ptprk protein tyrosine phosphatase, receptor type, K protein_coding Mus_musculus

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