C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein tyrosine phosphatase, receptor type, K
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368226 PTPRK-003 ENSG00000152894 9606 - 6:127968779-128520674 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368226
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368226 6.291±0.00 2.984±0.00 1.535±0.00 4.542±0.07 3.570±0.76 4.363±0.77 3.590±0.00 5.262±0.77 2.979±1.37 4.799±2.63 0.941±0.00 8.498±0.50 6.303±1.35 3.081±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001EN CIL_0001EN_0002 CGP 6:127708072-128520674

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004725 IDA:IEA protein tyrosine phosphatase activity
GO:0005001 NAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005887 NAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006470 IDA:IEA protein dephosphorylation
GO:0007155 IMP cell adhesion
GO:0007165 IDA signal transduction
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0008013 IPI beta-catenin binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0010839 IDA negative regulation of keratinocyte proliferation
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016477 IMP cell migration
GO:0016791 IEA phosphatase activity
GO:0019901 IPI protein kinase binding
GO:0030336 IDA negative regulation of cell migration
GO:0031256 IDA leading edge membrane
GO:0034394 IDA protein localization to cell surface
GO:0034614 IDA cellular response to reactive oxygen species
GO:0034644 IDA cellular response to UV
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0045295 IPI gamma-catenin binding
GO:0045786 IDA negative regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0048041 IMP focal adhesion assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000166468 Ptprk-201 protein_coding Mus_musculus 0 3308

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