C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: junctional adhesion molecule 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154721 JAM2 9606 + 21:25639272-25717562 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312957 JAM2-201 25639282-25717552 protein_coding
  ENST00000400532 JAM2-003 25639272-25714573 protein_coding
  ENST00000460679 JAM2-007 25689866-25714731 nonsense_mediated_decay
  ENST00000471689 JAM2-009 25712019-25714889 retained_intron
  ENST00000477351 JAM2-008 25711388-25714739 processed_transcript
  ENST00000480456 JAM2-001 25639272-25717562 protein_coding
  ENST00000492962 JAM2-006 25702178-25710179 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000312957ENST00000400532ENST00000460679ENST00000480456
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000312957 N/A N/A N/A N/A 12.323±0.00 N/A N/A N/A 1.486±0.00 N/A N/A 6.328±0.00
ENST00000400532 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 41.522±1.56 N/A
ENST00000460679 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 51.044±4.71 N/A
ENST00000480456 6.081±0.00 7.372±0.00 7.664±2.47 5.807±3.30 7.546±5.60 3.043±0.00 3.120±0.00 7.547±4.62 N/A 8.802±4.38 26.392±8.39 12.285±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000R8 CIL_0000R8_0001 CGP 21:25585656-25717562
CIL_0000ML CIL_0000ML_0002 CGP 21:25639272-25735673

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0005923 IEA tight junction
GO:0007162 IEA negative regulation of cell adhesion
GO:0007596 TAS blood coagulation
GO:0016337 NAS single organismal cell-cell adhesion
GO:0030198 TAS extracellular matrix organization
GO:0046982 IEA protein heterodimerization activity
GO:0050900 TAS leukocyte migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058996 jam2a junctional adhesion molecule 2a protein_coding Danio_rerio
ENSDARG00000079071 jam2b junctional adhesion molecule 2b protein_coding Danio_rerio
ENSMUSG00000053062 Jam2 junction adhesion molecule 2 protein_coding Mus_musculus

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