C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155666 KDM8 9606 + 16:27203495-27221768 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000286096 KDM8-001 27203495-27221768 protein_coding
  ENST00000441782 KDM8-002 27203975-27220859 protein_coding
  ENST00000562269 KDM8-012 27203517-27213642 processed_transcript
  ENST00000562733 KDM8-014 27203996-27210483 protein_coding
  ENST00000563571 KDM8-009 27214576-27219063 retained_intron
  ENST00000563881 KDM8-015 27204078-27204444 processed_transcript
  ENST00000564961 KDM8-004 27203508-27211715 retained_intron
  ENST00000567366 KDM8-008 27214620-27220667 processed_transcript
  ENST00000567735 KDM8-011 27214971-27221194 protein_coding
  ENST00000567785 KDM8-005 27214612-27221084 processed_transcript
  ENST00000568792 KDM8-007 27214638-27216134 retained_intron
  ENST00000568965 KDM8-003 27210124-27221722 protein_coding
  ENST00000569329 KDM8-013 27203803-27210612 protein_coding
  ENST00000569592 KDM8-010 27220318-27220902 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000286096ENST00000441782ENST00000562269ENST00000562733ENST00000564961ENST00000567366ENST00000567735ENST00000568965ENST00000569329ENST00000569592
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000286096 0.275±0.00 1.410±0.00 N/A N/A 0.202±0.00 N/A 0.258±0.15 N/A 4.529±0.00 0.222±0.10 N/A 1.447±0.50 0.892±0.39 0.515±0.17
ENST00000441782 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.430±0.00 N/A N/A
ENST00000562269 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.114±0.00 N/A N/A N/A
ENST00000562733 N/A N/A 0.639±0.00 N/A N/A N/A 0.288±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000564961 N/A N/A N/A N/A 0.112±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000567366 0.361±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000567735 N/A N/A N/A N/A 0.405±0.00 0.550±0.00 N/A N/A N/A N/A 0.469±0.00 N/A N/A N/A
ENST00000568965 0.345±0.00 N/A N/A 0.419±0.08 0.453±0.00 0.106±0.00 0.253±0.00 1.274±0.00 N/A N/A 0.243±0.05 1.152±0.36 1.115±0.00 1.752±0.99
ENST00000569329 N/A N/A N/A N/A 0.062±0.00 N/A N/A N/A N/A 1.147±0.00 N/A N/A N/A N/A
ENST00000569592 N/A N/A N/A N/A N/A 0.386±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003V9 CIL_0003V9_0002 CGP 16:27203495-27268794

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IMP G2/M transition of mitotic cell cycle
GO:0003682 IDA chromatin binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0051864 IDA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IDA histone H3-K36 demethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037844 kdm8 lysine (K)-specific demethylase 8 protein_coding Danio_rerio
ENSMUSG00000030752 Kdm8 lysine (K)-specific demethylase 8 protein_coding Mus_musculus

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