C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-cell lymphoma invasion and metastasis 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000156299 TIAM1 9606 - 21:31118416-31559977 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000286827 TIAM1-001 31118416-31558977 protein_coding
  ENST00000423206 TIAM1-005 31118418-31130221 protein_coding
  ENST00000455508 TIAM1-003 31266296-31344279 protein_coding
  ENST00000469412 TIAM1-002 31212631-31559977 processed_transcript
  ENST00000491927 TIAM1-004 31123939-31130306 retained_intron
  ENST00000541036 TIAM1-201 31118418-31558977 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryTestisENST00000286827ENST00000455508ENST00000469412ENST00000541036
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000286827 N/A N/A 0.055±0.00 N/A N/A N/A 1.317±0.00 N/A 2.139±0.00 N/A 0.346±0.11 2.352±1.15
ENST00000455508 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.063±0.00 1.261±0.00 N/A
ENST00000469412 N/A N/A N/A N/A N/A 0.096±0.00 N/A N/A N/A N/A N/A N/A
ENST00000541036 0.520±0.00 0.926±0.00 N/A 5.823±0.00 0.534±0.08 0.057±0.00 0.471±0.00 0.260±0.00 0.773±0.00 0.028±0.00 0.262±0.00 1.780±0.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000886 CIL_000886_0001 VISTA 21:30978528-31579396
CIL_0000MO CIL_0000MO_0002 CGP 21:31118416-31668931

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005057 IEA receptor signaling protein activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 TAS:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005543 IEA phospholipid binding
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0007160 IMP cell-matrix adhesion
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0016477 IMP cell migration
GO:0016601 IMP Rac protein signal transduction
GO:0030676 IMP Rac guanyl-nucleotide exchange factor activity
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0032321 TAS positive regulation of Rho GTPase activity
GO:0032855 IMP positive regulation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0044291 IDA cell-cell contact zone
GO:0046875 IEA ephrin receptor binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048013 IEA ephrin receptor signaling pathway
GO:0050772 IEA positive regulation of axonogenesis
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025920 TIAM1 (1 of 2) T-cell lymphoma invasion and metastasis 1 protein_coding Danio_rerio
ENSDARG00000078430 tiam1a T-cell lymphoma invasion and metastasis 1a protein_coding Danio_rerio
ENSMUSG00000002489 Tiam1 T cell lymphoma invasion and metastasis 1 protein_coding Mus_musculus

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