C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: T-cell lymphoma invasion and metastasis 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000286827 TIAM1-001 ENSG00000156299 9606 - 21:31118416-31558977 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderKidneyLungOvaryTestisENST00000286827
Transcript ID Bladder Kidney Lung Ovary Testis
ENST00000286827 0.055±0.00 1.317±0.00 2.139±0.00 0.346±0.11 2.352±1.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000886 CIL_000886_0001 VISTA 21:30978528-31579396
CIL_0000MO CIL_0000MO_0002 CGP 21:31118416-31668931

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005057 IEA receptor signaling protein activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 TAS:IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005543 IEA phospholipid binding
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0007160 IMP cell-matrix adhesion
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0016477 IMP cell migration
GO:0016601 IMP Rac protein signal transduction
GO:0030676 IMP Rac guanyl-nucleotide exchange factor activity
GO:0031234 IDA extrinsic component of cytoplasmic side of plasma membrane
GO:0032321 TAS positive regulation of Rho GTPase activity
GO:0032855 IMP positive regulation of Rac GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0044291 IDA cell-cell contact zone
GO:0046875 IEA ephrin receptor binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048013 IEA ephrin receptor signaling pathway
GO:0050772 IEA positive regulation of axonogenesis
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002588 Tiam1-201 protein_coding Mus_musculus 0 6355
ENSMUST00000163370 Tiam1-202 protein_coding Mus_musculus 0 6355
ENSMUST00000114124 Tiam1-001 protein_coding Mus_musculus 0 6355
ENSMUST00000114122 Tiam1-009 protein_coding Mus_musculus 0 3338
ENSMUST00000089084 Tiam1-013 retained_intron Mus_musculus 0 2918
ENSMUST00000164263 Tiam1-003 protein_coding Mus_musculus 0 2388
ENSMUST00000178095 Tiam1-012 processed_transcript Mus_musculus 0 1116
ENSMUST00000151655 Tiam1-011 processed_transcript Mus_musculus 0 529
ENSDART00000089694 TIAM1 (1 of 2)-201 protein_coding Danio_rerio 0 527
ENSMUST00000130951 Tiam1-008 processed_transcript Mus_musculus 0 329
ENSMUST00000139544 Tiam1-005 processed_transcript Mus_musculus 0 303
ENSMUST00000144691 Tiam1-010 protein_coding Mus_musculus 0.000000001 71

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