C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T cell lymphoma invasion and metastasis 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002489 Tiam1 10090 - 16:89787111-89980080 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002588 Tiam1-201 89787111-89960827 protein_coding
  ENSMUST00000089084 Tiam1-013 89787858-89837875 retained_intron
  ENSMUST00000114122 Tiam1-009 89787111-89857817 protein_coding
  ENSMUST00000114124 Tiam1-001 89787111-89974699 protein_coding
  ENSMUST00000124433 Tiam1-002 89908221-89956107 retained_intron
  ENSMUST00000130951 Tiam1-008 89898351-89960737 processed_transcript
  ENSMUST00000134021 Tiam1-004 89791685-89799990 protein_coding
  ENSMUST00000136760 Tiam1-006 89955965-89980080 processed_transcript
  ENSMUST00000139544 Tiam1-005 89898421-89918985 processed_transcript
  ENSMUST00000144691 Tiam1-010 89787116-89798041 protein_coding
  ENSMUST00000151655 Tiam1-011 89898310-89974699 processed_transcript
  ENSMUST00000155915 Tiam1-007 89908548-89973899 processed_transcript
  ENSMUST00000163370 Tiam1-202 89787111-89974699 protein_coding
  ENSMUST00000164263 Tiam1-003 89787730-89818352 protein_coding
  ENSMUST00000178095 Tiam1-012 89788422-89795282 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002588ENSMUST00000089084ENSMUST00000114122ENSMUST00000114124ENSMUST00000134021ENSMUST00000144691ENSMUST00000163370ENSMUST00000164263ENSMUST00000178095
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002588 0.707±0.00 1.307±0.00 2.567±0.00 4.165±3.15 0.250±0.00 N/A 0.749±0.00 N/A 0.120±0.00 1.464±0.73 N/A 1.125±0.30 1.923±1.35 N/A
ENSMUST00000089084 0.591±0.26 1.865±0.08 N/A 13.562±0.00 0.881±0.29 0.779±0.11 0.252±0.00 N/A N/A 0.734±0.12 N/A 1.263±0.94 5.617±3.72 4.710±0.00
ENSMUST00000114122 N/A N/A N/A N/A 0.163±0.00 N/A N/A N/A 0.106±0.06 N/A N/A 1.087±0.14 N/A 1.066±0.00
ENSMUST00000114124 N/A N/A N/A N/A N/A N/A N/A 0.263±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000134021 N/A N/A N/A N/A N/A N/A N/A N/A 0.089±0.00 N/A N/A N/A N/A N/A
ENSMUST00000144691 N/A N/A N/A N/A N/A N/A N/A N/A 0.642±0.00 N/A N/A N/A N/A N/A
ENSMUST00000163370 0.269±0.06 2.210±0.78 N/A 3.055±0.00 0.353±0.15 0.534±0.05 0.149±0.00 0.426±0.11 0.138±0.18 1.033±0.00 N/A 0.827±0.37 N/A 0.685±0.00
ENSMUST00000164263 N/A N/A N/A 3.838±2.57 N/A N/A N/A 0.323±0.05 0.095±0.06 2.012±0.80 1.481±0.68 N/A N/A N/A
ENSMUST00000178095 N/A N/A N/A N/A N/A 0.789±0.00 N/A N/A 0.210±0.05 1.369±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000886 CIL_000886_0002 VISTA 16:89609485-90210340
CIL_0000MO CIL_0000MO_0003 CGP 16:89787111-90226322

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005057 IEA receptor signaling protein activity
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005543 IDA phospholipid binding
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0007160 IEA cell-matrix adhesion
GO:0007264 IDA small GTPase mediated signal transduction
GO:0016477 IEA cell migration
GO:0016601 IEA Rac protein signal transduction
GO:0030676 IEA Rac guanyl-nucleotide exchange factor activity
GO:0031234 IEA extrinsic component of cytoplasmic side of plasma membrane
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0043547 IDA positive regulation of GTPase activity
GO:0044291 IEA cell-cell contact zone
GO:0046875 IPI ephrin receptor binding
GO:0048013 IDA ephrin receptor signaling pathway
GO:0050772 IMP positive regulation of axonogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025920 TIAM1 (1 of 2) T-cell lymphoma invasion and metastasis 1 protein_coding Danio_rerio
ENSDARG00000078430 tiam1a T-cell lymphoma invasion and metastasis 1a protein_coding Danio_rerio
ENSG00000156299 TIAM1 T-cell lymphoma invasion and metastasis 1 protein_coding Homo_sapiens

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