C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 4A2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000156976 EIF4A2 9606 + 3:186783205-186789900 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323963 EIF4A2-001 186783547-186789900 protein_coding
  ENST00000425053 EIF4A2-003 186783577-186789881 nonsense_mediated_decay
  ENST00000426808 EIF4A2-002 186783572-186789897 nonsense_mediated_decay
  ENST00000429589 EIF4A2-016 186783577-186789140 nonsense_mediated_decay
  ENST00000440191 EIF4A2-004 186783577-186789897 protein_coding
  ENST00000441007 EIF4A2-008 186783205-186784659 protein_coding
  ENST00000443963 EIF4A2-005 186783597-186789897 nonsense_mediated_decay
  ENST00000445596 EIF4A2-009 186783305-186785047 protein_coding
  ENST00000461021 EIF4A2-026 186787407-186788199 retained_intron
  ENST00000465032 EIF4A2-013 186783577-186785297 retained_intron
  ENST00000465222 EIF4A2-010 186783575-186785042 retained_intron
  ENST00000465267 EIF4A2-014 186783577-186785770 retained_intron
  ENST00000465792 EIF4A2-022 186786076-186787290 retained_intron
  ENST00000466362 EIF4A2-020 186785061-186786498 retained_intron
  ENST00000467585 EIF4A2-019 186784203-186786044 retained_intron
  ENST00000468362 EIF4A2-007 186785962-186788368 retained_intron
  ENST00000475409 EIF4A2-023 186786491-186787522 retained_intron
  ENST00000475653 EIF4A2-017 186783593-186787386 retained_intron
  ENST00000485101 EIF4A2-006 186783578-186789894 retained_intron
  ENST00000486805 EIF4A2-012 186783577-186785041 retained_intron
  ENST00000491473 EIF4A2-011 186783577-186784944 retained_intron
  ENST00000492144 EIF4A2-021 186785995-186788256 retained_intron
  ENST00000494445 EIF4A2-025 186787314-186789291 retained_intron
  ENST00000495049 EIF4A2-015 186783577-186786216 retained_intron
  ENST00000496382 EIF4A2-027 186787776-186789477 retained_intron
  ENST00000497177 EIF4A2-024 186786640-186788507 retained_intron
  ENST00000498746 EIF4A2-018 186784203-186785913 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000323963ENST00000425053ENST00000426808ENST00000440191ENST00000485101ENST00000496382
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000323963 24.844±0.00 24.376±0.00 23.676±0.00 138.948±5.32 45.913±0.00 111.074±74.09 52.085±8.59 22.055±11.49 73.293±0.00 53.385±11.23 70.804±38.85 132.099±0.00 22.665±1.87 122.329±0.00
ENST00000425053 12.165±0.00 31.230±0.00 N/A N/A 18.627±0.98 N/A N/A N/A 11.315±0.00 N/A N/A 101.324±39.25 N/A N/A
ENST00000426808 13.356±0.00 42.927±0.00 N/A 52.923±0.00 N/A N/A N/A 24.162±0.00 8.757±0.00 42.288±0.00 N/A 70.555±0.00 116.289±0.00 179.725±0.00
ENST00000440191 15.523±0.00 N/A 30.411±0.00 92.834±3.98 33.662±1.09 46.983±20.33 26.358±2.68 34.408±0.83 8.775±0.00 40.284±16.33 76.661±0.00 88.232±28.25 62.292±0.93 63.392±0.00
ENST00000485101 N/A N/A N/A N/A 12.184±0.00 10.399±0.00 N/A 4.030±0.00 N/A 11.897±0.00 N/A 37.744±0.00 N/A N/A
ENST00000496382 N/A N/A N/A 285.435±85.24 N/A 193.898±0.00 N/A 79.926±3.82 146.241±0.00 116.762±0.00 100.265±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LA CIL_0008LA_0001 VISTA 3:186647123-187250687
CIL_000042 CIL_000042_0001 CGP 3:186717276-186789900
CIL_000041 CIL_000041_0001 CGP 3:186783205-186807058

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003743 IEA translation initiation factor activity
GO:0004386 TAS helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006200 IEA ATP catabolic process
GO:0006412 TAS translation
GO:0006413 TAS translational initiation
GO:0006446 TAS regulation of translational initiation
GO:0008026 IEA ATP-dependent helicase activity
GO:0010467 TAS gene expression
GO:0016032 IEA viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0016281 TAS eukaryotic translation initiation factor 4F complex
GO:0016787 IEA hydrolase activity
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016477 eif4a2 eukaryotic translation initiation factor 4A, isoform 2 protein_coding Danio_rerio
ENSMUSG00000022884 Eif4a2 eukaryotic translation initiation factor 4A2 protein_coding Mus_musculus

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