C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157404 KIT 9606 + 4:54657918-54740715 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000288135 KIT-001 54657918-54740715 protein_coding
  ENST00000412167 KIT-002 54657918-54739011 protein_coding
  ENST00000512959 KIT-004 54729292-54733401 retained_intron
  ENST00000514582 KIT-003 54657939-54695906 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartLungOvaryPlacentaTestisENST00000288135ENST00000412167ENST00000514582
Transcript ID Adipose Brain Breast Colon Heart Lung Ovary Placenta Testis
ENST00000288135 2.362±0.00 2.212±0.00 2.271±0.00 7.698±0.00 0.370±0.00 1.654±0.00 1.353±0.00 0.526±0.10 1.969±1.30
ENST00000412167 N/A N/A 3.405±0.00 N/A 0.405±0.00 1.445±0.00 N/A N/A N/A
ENST00000514582 N/A N/A N/A N/A N/A N/A N/A 1.195±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CJ CIL_0001CJ_0001 CGP 4:54229097-54740715
CIL_0001CK CIL_0001CK_0001 CGP 4:54657918-55125589

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0001541 ISS ovarian follicle development
GO:0001669 IEA acrosomal vesicle
GO:0002020 IEA protease binding
GO:0002318 IEA myeloid progenitor cell differentiation
GO:0002320 IEA lymphoid progenitor cell differentiation
GO:0002327 ISS immature B cell differentiation
GO:0002371 ISS dendritic cell cytokine production
GO:0002551 IDA mast cell chemotaxis
GO:0002573 IEA myeloid leukocyte differentiation
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004714 IDA:IEA transmembrane receptor protein tyrosine kinase activity
GO:0004716 IEA receptor signaling protein tyrosine kinase activity
GO:0005020 IEA stem cell factor receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005911 IEA cell-cell junction
GO:0006468 IEA protein phosphorylation
GO:0006687 IEA glycosphingolipid metabolic process
GO:0006954 ISS inflammatory response
GO:0007165 TAS signal transduction
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007283 ISS spermatogenesis
GO:0007286 IEA spermatid development
GO:0008284 IEA positive regulation of cell proliferation
GO:0008354 IEA germ cell migration
GO:0008360 ISS regulation of cell shape
GO:0008542 IEA visual learning
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008584 IEP male gonad development
GO:0009314 IEA response to radiation
GO:0009897 IEA external side of plasma membrane
GO:0009898 IEA cytoplasmic side of plasma membrane
GO:0009986 IEA cell surface
GO:0010628 IEA positive regulation of gene expression
GO:0010863 TAS positive regulation of phospholipase C activity
GO:0014068 TAS positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019827 TAS stem cell maintenance
GO:0019955 IDA cytokine binding
GO:0023014 IEA signal transduction by phosphorylation
GO:0030032 ISS lamellipodium assembly
GO:0030097 TAS hemopoiesis
GO:0030217 ISS T cell differentiation
GO:0030218 ISS erythrocyte differentiation
GO:0030318 ISS melanocyte differentiation
GO:0030335 IEA positive regulation of cell migration
GO:0031274 IEA positive regulation of pseudopodium assembly
GO:0031532 IDA actin cytoskeleton reorganization
GO:0032762 IDA mast cell cytokine production
GO:0035019 IEA somatic stem cell maintenance
GO:0035162 ISS embryonic hemopoiesis
GO:0035234 IEA ectopic germ cell programmed cell death
GO:0035556 IEA intracellular signal transduction
GO:0035855 ISS megakaryocyte development
GO:0038093 IDA Fc receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038109 IDA Kit signaling pathway
GO:0038162 ISS erythropoietin-mediated signaling pathway
GO:0042127 TAS regulation of cell proliferation
GO:0042511 IMP positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517 IMP positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523 IMP positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0042629 IMP mast cell granule
GO:0042803 IPI protein homodimerization activity
GO:0043069 IEA negative regulation of programmed cell death
GO:0043303 IMP mast cell degranulation
GO:0043406 IEA positive regulation of MAP kinase activity
GO:0043410 IMP positive regulation of MAPK cascade
GO:0043473 ISS pigmentation
GO:0043552 TAS positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 TAS innate immune response
GO:0045747 IEA positive regulation of Notch signaling pathway
GO:0046427 IMP positive regulation of JAK-STAT cascade
GO:0046777 IDA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048066 IEA developmental pigmentation
GO:0048070 IEA regulation of developmental pigmentation
GO:0048103 IEA somatic stem cell division
GO:0048170 IEA positive regulation of long-term neuronal synaptic plasticity
GO:0048565 ISS digestive tract development
GO:0048863 ISS stem cell differentiation
GO:0050673 IEA epithelial cell proliferation
GO:0050910 ISS detection of mechanical stimulus involved in sensory perception of sound
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060326 IDA cell chemotaxis
GO:0060374 ISS mast cell differentiation
GO:0070662 TAS mast cell proliferation
GO:0097067 IEA cellular response to thyroid hormone stimulus
GO:0097324 ISS melanocyte migration
GO:0097326 ISS melanocyte adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043317 kita kit receptor a protein_coding Danio_rerio
ENSDARG00000056133 kitb kit receptor b protein_coding Danio_rerio
ENSMUSG00000005672 Kit kit oncogene protein_coding Mus_musculus

Loading