C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000412167 KIT-002 ENSG00000157404 9606 + 4:54657918-54739011 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartLungENST00000412167
Transcript ID Breast Heart Lung
ENST00000412167 3.405±0.00 0.405±0.00 1.445±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CJ CIL_0001CJ_0001 CGP 4:54229097-54740715
CIL_0001CK CIL_0001CK_0001 CGP 4:54657918-55125589

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0001541 ISS ovarian follicle development
GO:0002327 ISS immature B cell differentiation
GO:0002371 ISS dendritic cell cytokine production
GO:0002551 IDA mast cell chemotaxis
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004714 IDA:IEA transmembrane receptor protein tyrosine kinase activity
GO:0004716 IEA receptor signaling protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006954 ISS inflammatory response
GO:0007165 TAS signal transduction
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007283 ISS spermatogenesis
GO:0008360 ISS regulation of cell shape
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008584 IEP male gonad development
GO:0010863 TAS positive regulation of phospholipase C activity
GO:0014068 TAS positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019827 TAS stem cell maintenance
GO:0019955 IDA cytokine binding
GO:0023014 IEA signal transduction by phosphorylation
GO:0030032 ISS lamellipodium assembly
GO:0030097 TAS hemopoiesis
GO:0030217 ISS T cell differentiation
GO:0030218 ISS erythrocyte differentiation
GO:0030318 ISS melanocyte differentiation
GO:0031532 IDA actin cytoskeleton reorganization
GO:0032762 IDA mast cell cytokine production
GO:0035162 ISS embryonic hemopoiesis
GO:0035855 ISS megakaryocyte development
GO:0038093 IDA Fc receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038109 IDA Kit signaling pathway
GO:0038162 ISS erythropoietin-mediated signaling pathway
GO:0042127 TAS regulation of cell proliferation
GO:0042511 IMP positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517 IMP positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523 IMP positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0042629 IMP mast cell granule
GO:0042803 IPI protein homodimerization activity
GO:0043303 IMP mast cell degranulation
GO:0043410 IMP positive regulation of MAPK cascade
GO:0043473 ISS pigmentation
GO:0043552 TAS positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 TAS innate immune response
GO:0046427 IMP positive regulation of JAK-STAT cascade
GO:0046777 IDA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048565 ISS digestive tract development
GO:0048863 ISS stem cell differentiation
GO:0050910 ISS detection of mechanical stimulus involved in sensory perception of sound
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060326 IDA cell chemotaxis
GO:0060374 ISS mast cell differentiation
GO:0070662 TAS mast cell proliferation
GO:0097324 ISS melanocyte migration
GO:0097326 ISS melanocyte adhesion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000144270 Kit-001 protein_coding Mus_musculus 0 2680
ENSMUST00000005815 Kit-002 protein_coding Mus_musculus 0 2625
ENSMUST00000148993 Kit-003 processed_transcript Mus_musculus 0 817
ENSMUST00000136002 Kit-004 processed_transcript Mus_musculus 0 398
ENSMUST00000143221 Kit-006 processed_transcript Mus_musculus 0 344

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