C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuregulin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158458 NRG2 9606 - 5:139846779-140043299 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289409 NRG2-002 139847917-140043069 protein_coding
  ENST00000289422 NRG2-012 139847649-140043147 protein_coding
  ENST00000340391 NRG2-006 139847917-139904397 protein_coding
  ENST00000358522 NRG2-007 139847917-140043069 protein_coding
  ENST00000361474 NRG2-001 139847675-140043294 protein_coding
  ENST00000378238 NRG2-011 139851753-140043069 nonsense_mediated_decay
  ENST00000518130 NRG2-010 139869538-139904310 processed_transcript
  ENST00000519478 NRG2-009 139869399-139871803 processed_transcript
  ENST00000541337 NRG2-201 139846779-140043299 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000289409ENST00000289422ENST00000340391ENST00000361474ENST00000378238ENST00000518130ENST00000541337
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000289409 N/A N/A N/A 0.583±0.00 N/A N/A 0.415±0.00 N/A 0.076±0.00 N/A 1.274±0.00 N/A 0.427±0.25 N/A
ENST00000289422 N/A N/A N/A N/A 0.226±0.00 N/A N/A N/A N/A 0.081±0.00 N/A N/A N/A N/A
ENST00000340391 1.817±0.00 N/A 0.283±0.00 N/A N/A 0.609±0.00 N/A 0.317±0.00 0.061±0.00 N/A 1.102±0.00 3.675±2.98 0.177±0.01 0.493±0.00
ENST00000361474 N/A N/A N/A 0.383±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000378238 N/A 0.542±0.00 N/A N/A 1.062±0.00 0.818±0.00 N/A N/A 0.494±0.00 N/A 0.690±0.00 0.838±0.75 N/A 0.729±0.00
ENST00000518130 N/A N/A N/A 0.820±0.00 N/A N/A 0.231±0.00 N/A N/A N/A 0.651±0.00 0.194±0.00 N/A 0.973±0.00
ENST00000541337 N/A 0.349±0.00 N/A N/A N/A 0.515±0.50 0.021±0.00 N/A N/A 0.150±0.00 N/A 0.026±0.00 0.124±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000540 CIL_000540_0001 CGP 5:139795821-140043299
CIL_00062Q CIL_00062Q_0002 CGP 5:139846779-140125619

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS:IEA receptor binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005886 IEA plasma membrane
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009790 IEA embryo development
GO:0016021 IEA integral component of membrane
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077818 nrg2a neuregulin 2a protein_coding Danio_rerio
ENSDARG00000086585 nrg2b neuregulin 2b protein_coding Danio_rerio
ENSMUSG00000060275 Nrg2 neuregulin 2 protein_coding Mus_musculus

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