C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of G-protein signaling 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159788 RGS12 9606 + 4:3293028-3439913 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336727 RGS12-201 3316068-3439911 protein_coding
  ENST00000338806 RGS12-003 3369879-3439905 protein_coding
  ENST00000344733 RGS12-001 3314147-3439905 protein_coding
  ENST00000382788 RGS12-002 3316068-3432250 protein_coding
  ENST00000502947 RGS12-016 3316068-3343189 retained_intron
  ENST00000503041 RGS12-019 3385699-3414844 processed_transcript
  ENST00000504194 RGS12-008 3385971-3439905 retained_intron
  ENST00000504559 RGS12-024 3422930-3423641 processed_transcript
  ENST00000505570 RGS12-017 3385604-3414242 processed_transcript
  ENST00000506631 RGS12-009 3293028-3418119 retained_intron
  ENST00000506998 RGS12-005 3370186-3418267 retained_intron
  ENST00000507041 RGS12-021 3422535-3430447 retained_intron
  ENST00000507246 RGS12-026 3422553-3428142 processed_transcript
  ENST00000508158 RGS12-015 3385146-3428598 processed_transcript
  ENST00000509746 RGS12-027 3422515-3423865 retained_intron
  ENST00000509772 RGS12-029 3428089-3439913 processed_transcript
  ENST00000510803 RGS12-028 3420388-3422524 retained_intron
  ENST00000511709 RGS12-025 3422535-3423641 processed_transcript
  ENST00000511805 RGS12-014 3318039-3378591 processed_transcript
  ENST00000512266 RGS12-006 3412986-3419510 retained_intron
  ENST00000512990 RGS12-018 3385681-3414241 processed_transcript
  ENST00000513784 RGS12-013 3342415-3416121 processed_transcript
  ENST00000513991 RGS12-004 3413229-3428475 retained_intron
  ENST00000514268 RGS12-011 3316068-3417450 nonsense_mediated_decay
  ENST00000515521 RGS12-023 3417513-3428137 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336727ENST00000338806ENST00000344733ENST00000382788ENST00000502947ENST00000504194ENST00000507041ENST00000511805ENST00000512266ENST00000515521
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336727 0.872±0.00 N/A N/A 1.919±0.00 N/A N/A 0.525±0.00 N/A N/A N/A 2.576±0.00 N/A N/A N/A
ENST00000338806 N/A N/A 0.499±0.00 0.811±0.00 N/A N/A N/A N/A N/A N/A N/A 0.297±0.00 N/A N/A
ENST00000344733 N/A N/A N/A N/A 0.247±0.00 N/A N/A 0.442±0.00 N/A N/A N/A N/A N/A N/A
ENST00000382788 2.257±0.00 1.170±0.00 0.772±0.00 1.950±0.87 1.723±0.99 1.757±1.37 0.655±0.43 0.527±0.00 0.646±0.00 4.198±0.00 1.508±1.18 3.204±2.48 2.265±0.70 5.235±0.35
ENST00000502947 N/A N/A N/A N/A 1.095±0.00 2.078±0.00 N/A N/A 1.250±0.00 1.730±0.00 N/A 1.413±0.00 N/A N/A
ENST00000504194 N/A N/A N/A N/A N/A 0.481±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000507041 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.998±0.00 N/A N/A N/A
ENST00000511805 N/A N/A N/A N/A 2.051±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000512266 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.929±0.62 N/A N/A
ENST00000515521 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.258±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003Z3 CIL_0003Z3_0001 CGP 4:3244369-3439913
CIL_0001XB CIL_0001XB_0001 CGP 4:3293028-3449495

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000794 TAS condensed nuclear chromosome
GO:0005057 IEA receptor signaling protein activity
GO:0005096 IBA GTPase activator activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA:IBA cytoplasm
GO:0005886 IBA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0008277 TAS:IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0030695 IDA:IEA GTPase regulator activity
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043547 IBA positive regulation of GTPase activity
GO:0050790 IDA regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009610 rgs12a regulator of G-protein signaling 12a protein_coding Danio_rerio
ENSDARG00000036774 rgs12b regulator of G-protein signaling 12b protein_coding Danio_rerio
ENSMUSG00000029101 Rgs12 regulator of G-protein signaling 12 protein_coding Mus_musculus

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