C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family G (WHITE), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160179 ABCG1 9606 + 21:42199689-42297244 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343687 ABCG1-005 42219821-42297244 protein_coding
  ENST00000347800 ABCG1-004 42216077-42297244 protein_coding
  ENST00000361802 ABCG1-006 42219118-42297244 protein_coding
  ENST00000398437 ABCG1-008 42256084-42297244 protein_coding
  ENST00000398449 ABCG1-001 42219118-42297244 protein_coding
  ENST00000398457 ABCG1-002 42199689-42297244 protein_coding
  ENST00000450121 ABCG1-010 42219117-42284648 protein_coding
  ENST00000462050 ABCG1-003 42199812-42297244 processed_transcript
  ENST00000467818 ABCG1-011 42276686-42286141 retained_intron
  ENST00000472587 ABCG1-007 42276344-42297244 retained_intron
  ENST00000496783 ABCG1-009 42285934-42295352 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343687ENST00000347800ENST00000361802ENST00000398449ENST00000462050ENST00000467818ENST00000496783
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343687 N/A N/A N/A N/A N/A N/A N/A N/A 0.964±0.00 N/A N/A N/A N/A N/A
ENST00000347800 N/A N/A 2.386±0.00 N/A 2.180±0.00 1.138±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000361802 34.691±0.00 9.440±0.00 N/A 4.478±0.00 2.039±0.08 N/A N/A 1.746±0.00 1.228±0.00 13.980±0.00 7.128±3.20 1.549±0.00 4.066±2.23 1.296±0.00
ENST00000398449 15.677±0.00 8.119±0.00 N/A 2.870±1.06 2.192±0.25 6.019±3.17 2.175±0.52 3.085±1.12 2.268±0.00 9.326±0.02 14.836±0.00 3.658±2.23 8.017±1.42 1.913±0.00
ENST00000462050 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.345±0.00
ENST00000467818 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.447±0.00 N/A N/A
ENST00000496783 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.261±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036J CIL_00036J_0001 CGP 21:42062959-42297244
CIL_0004VV CIL_0004VV_0001 CGP 21:42199689-42315651

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005543 IC phospholipid binding
GO:0005548 IDA phospholipid transporter activity
GO:0005739 IDA mitochondrion
GO:0005768 ISS endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006810 IEA transport
GO:0008203 IDA cholesterol metabolic process
GO:0009720 NAS detection of hormone stimulus
GO:0009897 IDA external side of plasma membrane
GO:0010033 IDA response to organic substance
GO:0010745 TAS negative regulation of macrophage derived foam cell differentiation
GO:0010872 ISS regulation of cholesterol esterification
GO:0010875 IEA positive regulation of cholesterol efflux
GO:0010887 TAS negative regulation of cholesterol storage
GO:0010888 IEA negative regulation of lipid storage
GO:0015485 IC cholesterol binding
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0017127 IDA cholesterol transporter activity
GO:0019534 IDA toxin transporter activity
GO:0030301 IEA cholesterol transport
GO:0032367 IMP intracellular cholesterol transport
GO:0033344 IDA cholesterol efflux
GO:0033700 IMP phospholipid efflux
GO:0033993 IDA response to lipid
GO:0034041 IDA sterol-transporting ATPase activity
GO:0034374 ISS low-density lipoprotein particle remodeling
GO:0034375 ISS high-density lipoprotein particle remodeling
GO:0034436 IDA glycoprotein transport
GO:0034437 IDA glycoprotein transporter activity
GO:0042157 TAS lipoprotein metabolic process
GO:0042632 IDA cholesterol homeostasis
GO:0042803 IDA protein homodimerization activity
GO:0042987 IDA amyloid precursor protein catabolic process
GO:0043531 IDA ADP binding
GO:0043691 ISS reverse cholesterol transport
GO:0044281 TAS small molecule metabolic process
GO:0045542 ISS positive regulation of cholesterol biosynthetic process
GO:0046982 IPI protein heterodimerization activity
GO:0046983 NAS protein dimerization activity
GO:0055037 ISS recycling endosome
GO:0055085 TAS transmembrane transport
GO:0055091 IMP phospholipid homeostasis
GO:0055099 IEA response to high density lipoprotein particle
GO:1901998 IDA toxin transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063475 abcg1 ATP-binding cassette, sub-family G (WHITE), member 1 protein_coding Danio_rerio
ENSMUSG00000024030 Abcg1 ATP-binding cassette, sub-family G (WHITE), member 1 protein_coding Mus_musculus

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