C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATP-binding cassette, sub-family G (WHITE), member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000398449 ABCG1-001 ENSG00000160179 9606 + 21:42219118-42297244 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000398449
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000398449 15.677±0.00 8.119±0.00 2.870±1.06 2.192±0.25 6.019±3.17 2.175±0.52 3.085±1.12 2.268±0.00 9.326±0.02 14.836±0.00 3.658±2.23 8.017±1.42 1.913±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036J CIL_00036J_0001 CGP 21:42062959-42297244
CIL_0004VV CIL_0004VV_0001 CGP 21:42199689-42315651

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005543 IC phospholipid binding
GO:0005548 IDA phospholipid transporter activity
GO:0005739 IDA mitochondrion
GO:0005768 ISS endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006810 IEA transport
GO:0008203 IDA cholesterol metabolic process
GO:0009720 NAS detection of hormone stimulus
GO:0009897 IDA external side of plasma membrane
GO:0010033 IDA response to organic substance
GO:0010745 TAS negative regulation of macrophage derived foam cell differentiation
GO:0010872 ISS regulation of cholesterol esterification
GO:0010887 TAS negative regulation of cholesterol storage
GO:0015485 IC cholesterol binding
GO:0016020 IEA membrane
GO:0016887 IEA ATPase activity
GO:0017127 IDA cholesterol transporter activity
GO:0019534 IDA toxin transporter activity
GO:0032367 IMP intracellular cholesterol transport
GO:0033344 IDA cholesterol efflux
GO:0033700 IMP phospholipid efflux
GO:0033993 IDA response to lipid
GO:0034041 IDA sterol-transporting ATPase activity
GO:0034374 ISS low-density lipoprotein particle remodeling
GO:0034375 ISS high-density lipoprotein particle remodeling
GO:0034436 IDA glycoprotein transport
GO:0034437 IDA glycoprotein transporter activity
GO:0042157 TAS lipoprotein metabolic process
GO:0042632 IDA cholesterol homeostasis
GO:0042803 IDA protein homodimerization activity
GO:0042987 IDA amyloid precursor protein catabolic process
GO:0043531 IDA ADP binding
GO:0043691 ISS reverse cholesterol transport
GO:0044281 TAS small molecule metabolic process
GO:0045542 ISS positive regulation of cholesterol biosynthetic process
GO:0046982 IPI protein heterodimerization activity
GO:0046983 NAS protein dimerization activity
GO:0055037 ISS recycling endosome
GO:0055085 TAS transmembrane transport
GO:0055091 IMP phospholipid homeostasis
GO:1901998 IDA toxin transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000024829 Abcg1-001 protein_coding Mus_musculus 0 2383
ENSDART00000092809 abcg1-001 protein_coding Danio_rerio 0 1140
ENSMUST00000139013 Abcg1-002 retained_intron Mus_musculus 0 695
ENSMUST00000034648 Abcg4-003 protein_coding Mus_musculus 0 381
ENSMUST00000160323 Abcg4-002 processed_transcript Mus_musculus 0 381
ENSMUST00000161354 Abcg4-001 protein_coding Mus_musculus 0 381
ENSDART00000115051 abcg4b-001 protein_coding Danio_rerio 0 226
ENSDART00000152213 abcg4b-003 retained_intron Danio_rerio 0 209
ENSMUST00000161206 Abcg4-008 retained_intron Mus_musculus 0 195
ENSDART00000152583 abcg4b-002 retained_intron Danio_rerio 9e-23 113

Loading