C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family G (WHITE), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024030 Abcg1 10090 + 17:31057698-31115777 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024829 Abcg1-001 31057698-31115777 protein_coding
  ENSMUST00000139013 Abcg1-002 31057774-31098759 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024829
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024829 6.661±1.44 6.894±0.98 3.487±0.46 3.727±0.48 17.644±7.50 4.715±0.22 1.621±0.43 4.246±0.95 2.001±0.81 43.551±5.67 0.508±0.38 6.755±2.24 7.071±8.42 0.265±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036J CIL_00036J_0002 CGP 17:30954679-31115777
CIL_0008QJ CIL_0008QJ_0002 VISTA 17:31053737-31653776
CIL_0004VV CIL_0004VV_0002 CGP 17:31057698-31129646

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005548 IEA phospholipid transporter activity
GO:0005739 IEA mitochondrion
GO:0005768 IDA endosome
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0008203 IEA cholesterol metabolic process
GO:0009897 IDA external side of plasma membrane
GO:0010033 IEA response to organic substance
GO:0010745 IC negative regulation of macrophage derived foam cell differentiation
GO:0010872 IMP regulation of cholesterol esterification
GO:0010875 IDA positive regulation of cholesterol efflux
GO:0010888 IMP negative regulation of lipid storage
GO:0016021 IEA integral component of membrane
GO:0017127 IEA cholesterol transporter activity
GO:0019534 IEA toxin transporter activity
GO:0030301 IDA cholesterol transport
GO:0032367 IEA intracellular cholesterol transport
GO:0033344 IMP cholesterol efflux
GO:0033700 IEA phospholipid efflux
GO:0033993 IEA response to lipid
GO:0034041 IEA sterol-transporting ATPase activity
GO:0034374 IMP low-density lipoprotein particle remodeling
GO:0034375 IMP high-density lipoprotein particle remodeling
GO:0034436 IEA glycoprotein transport
GO:0034437 IEA glycoprotein transporter activity
GO:0042632 IEA cholesterol homeostasis
GO:0042803 IEA protein homodimerization activity
GO:0042987 IEA amyloid precursor protein catabolic process
GO:0043531 IEA ADP binding
GO:0043691 IMP reverse cholesterol transport
GO:0045542 IMP positive regulation of cholesterol biosynthetic process
GO:0046982 IEA protein heterodimerization activity
GO:0055037 IDA recycling endosome
GO:0055091 IEA phospholipid homeostasis
GO:0055099 IDA response to high density lipoprotein particle
GO:1901998 IEA toxin transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063475 abcg1 ATP-binding cassette, sub-family G (WHITE), member 1 protein_coding Danio_rerio
ENSG00000160179 ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 protein_coding Homo_sapiens

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