C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane protease, serine 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160183 TMPRSS3 9606 - 21:42371890-42396846 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000291532 TMPRSS3-001 42371890-42396846 protein_coding
  ENST00000398397 TMPRSS3-003 42381876-42396091 protein_coding
  ENST00000398405 TMPRSS3-004 42371890-42395943 protein_coding
  ENST00000433957 TMPRSS3-002 42371890-42396059 protein_coding
  ENST00000474596 TMPRSS3-006 42371890-42389118 processed_transcript
  ENST00000476848 TMPRSS3-007 42371890-42383751 retained_intron
  ENST00000478680 TMPRSS3-008 42381878-42382753 processed_transcript
  ENST00000482761 TMPRSS3-005 42371890-42390418 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000291532ENST00000398397ENST00000398405ENST00000433957ENST00000474596ENST00000476848ENST00000478680
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000291532 0.028±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000398397 N/A N/A 0.180±0.00 0.426±0.00 N/A N/A N/A N/A N/A 0.753±0.00 N/A 1.228±0.00 N/A N/A
ENST00000398405 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.061±0.00 0.047±0.00
ENST00000433957 N/A N/A N/A 0.072±0.00 0.547±0.00 0.020±0.00 N/A 0.161±0.00 0.104±0.00 N/A N/A 6.403±4.51 0.256±0.14 0.248±0.00
ENST00000474596 0.195±0.00 0.143±0.00 0.249±0.00 0.504±0.00 N/A 0.079±0.00 0.011±0.00 0.247±0.00 N/A N/A 0.039±0.00 5.014±3.56 0.135±0.09 N/A
ENST00000476848 N/A N/A N/A N/A 0.239±0.00 N/A N/A N/A 0.077±0.00 N/A N/A 4.266±0.00 N/A N/A
ENST00000478680 N/A N/A N/A N/A 2.025±0.00 N/A N/A N/A N/A 1.156±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QJ CIL_0008QJ_0001 VISTA 21:42290762-42894212
CIL_00036F CIL_00036F_0001 CGP 21:42362282-42396846
CIL_00036C CIL_00036C_0001 CGP 21:42371890-42447681

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 NAS:IEA serine-type endopeptidase activity
GO:0005044 IEA scavenger receptor activity
GO:0005515 IEA protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0006508 NAS:IEA proteolysis
GO:0006883 IDA cellular sodium ion homeostasis
GO:0006898 IEA receptor-mediated endocytosis
GO:0007605 IEA sensory perception of sound
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane
GO:0017080 IDA sodium channel regulator activity
GO:0043025 IEA neuronal cell body
GO:0070008 IEA serine-type exopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036545 TMPRSS3 (1 of 3) transmembrane protease, serine 3 protein_coding Danio_rerio
ENSDARG00000053315 tmprss3a transmembrane protease, serine 3a protein_coding Danio_rerio
ENSDARG00000090562 tmprss3a transmembrane protease, serine 3a protein_coding Danio_rerio
ENSMUSG00000024034 Tmprss3 transmembrane protease, serine 3 protein_coding Mus_musculus

Loading