C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160285 LSS 9606 - 21:46188141-46228824 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356396 LSS-002 46188141-46228822 protein_coding
  ENST00000397728 LSS-001 46188446-46228824 protein_coding
  ENST00000419093 LSS-008 46188474-46194580 protein_coding
  ENST00000450351 LSS-005 46216389-46228768 protein_coding
  ENST00000457828 LSS-201 46189124-46228824 protein_coding
  ENST00000464357 LSS-006 46215685-46228762 processed_transcript
  ENST00000472272 LSS-007 46227319-46228774 processed_transcript
  ENST00000474319 LSS-003 46189125-46193370 retained_intron
  ENST00000484808 LSS-009 46195676-46196371 processed_transcript
  ENST00000491729 LSS-004 46188446-46193487 retained_intron
  ENST00000522411 LSS-010 46190783-46228781 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397728ENST00000457828ENST00000474319ENST00000522411
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397728 N/A N/A N/A N/A N/A N/A N/A 0.712±0.00 N/A N/A N/A N/A N/A 3.684±0.00
ENST00000457828 14.848±0.00 7.366±0.00 0.178±0.00 12.156±10.33 15.606±14.65 6.258±4.59 7.798±0.00 7.149±3.64 8.472±7.30 5.439±4.91 5.911±4.41 30.246±11.61 8.690±3.24 15.325±4.68
ENST00000474319 N/A 1.423±0.00 N/A N/A N/A 0.984±0.00 N/A N/A N/A N/A N/A 5.614±0.00 N/A N/A
ENST00000522411 N/A N/A N/A N/A N/A 1.304±0.00 1.428±0.00 N/A N/A N/A 0.669±0.00 2.684±0.00 5.810±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000250 IEA lanosterol synthase activity
GO:0003824 IEA catalytic activity
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005811 IDA lipid particle
GO:0006695 IMP cholesterol biosynthetic process
GO:0008152 IEA metabolic process
GO:0008202 TAS steroid metabolic process
GO:0016020 IDA membrane
GO:0016866 IEA intramolecular transferase activity
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061274 lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) protein_coding Danio_rerio
ENSMUSG00000033105 Lss lanosterol synthase protein_coding Mus_musculus

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