C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: retinoblastoma binding protein 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162521 RBBP4 9606 + 1:32651142-32686211 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373485 RBBP4-002 32651234-32680657 protein_coding
  ENST00000373493 RBBP4-001 32651148-32686211 protein_coding
  ENST00000401893 RBBP4-017 32651210-32668579 retained_intron
  ENST00000414241 RBBP4-011 32651142-32680053 protein_coding
  ENST00000445722 RBBP4-013 32651487-32668281 protein_coding
  ENST00000458695 RBBP4-003 32651356-32680040 protein_coding
  ENST00000460669 RBBP4-009 32669107-32680653 nonsense_mediated_decay
  ENST00000463378 RBBP4-008 32669093-32679908 protein_coding
  ENST00000465780 RBBP4-005 32651226-32652506 retained_intron
  ENST00000475321 RBBP4-007 32668319-32672901 protein_coding
  ENST00000477563 RBBP4-006 32651278-32668337 nonsense_mediated_decay
  ENST00000482190 RBBP4-010 32669256-32680651 protein_coding
  ENST00000490500 RBBP4-004 32651485-32657572 protein_coding
  ENST00000492348 RBBP4-019 32651217-32680204 nonsense_mediated_decay
  ENST00000524393 RBBP4-015 32651214-32669102 processed_transcript
  ENST00000525506 RBBP4-020 32651218-32657674 retained_intron
  ENST00000526193 RBBP4-016 32651217-32669267 nonsense_mediated_decay
  ENST00000527118 RBBP4-014 32651178-32669088 nonsense_mediated_decay
  ENST00000531983 RBBP4-018 32668569-32669256 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373493ENST00000414241ENST00000458695ENST00000492348
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373493 3.769±0.00 5.109±0.00 0.850±0.00 5.062±1.64 3.151±1.29 2.822±0.26 1.074±0.00 3.112±1.32 1.827±0.21 2.609±0.58 3.035±2.13 5.782±1.74 2.233±0.06 6.258±1.25
ENST00000414241 9.358±0.00 N/A N/A N/A N/A N/A 6.478±0.00 N/A N/A N/A N/A 10.274±1.31 5.240±0.86 18.054±3.26
ENST00000458695 N/A N/A 2.210±0.00 N/A 4.397±0.00 7.426±0.00 N/A 6.062±0.00 6.561±0.00 7.563±0.00 N/A 7.907±0.00 6.953±2.90 N/A
ENST00000492348 16.049±0.00 20.099±0.00 3.096±0.00 13.967±7.24 14.743±5.84 13.991±7.93 7.960±3.97 15.538±9.13 7.133±0.32 13.542±6.15 20.959±0.00 17.514±4.66 13.446±4.44 40.587±1.64

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0006200 IDA ATP catabolic process
GO:0006260 IEA DNA replication
GO:0006334 TAS nucleosome assembly
GO:0006335 IDA DNA replication-dependent nucleosome assembly
GO:0006336 IDA DNA replication-independent nucleosome assembly
GO:0006338 IDA chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008094 IDA DNA-dependent ATPase activity
GO:0008285 TAS negative regulation of cell proliferation
GO:0016580 NAS Sin3 complex
GO:0016581 NAS NuRD complex
GO:0016589 IDA NURF complex
GO:0031492 IDA nucleosomal DNA binding
GO:0031497 IDA chromatin assembly
GO:0033186 IDA CAF-1 complex
GO:0034080 TAS CENP-A containing nucleosome assembly
GO:0035098 IDA ESC/E(Z) complex
GO:0042393 NAS histone binding
GO:0042826 IPI histone deacetylase binding
GO:0043044 IDA ATP-dependent chromatin remodeling
GO:0043234 IDA protein complex
GO:0051726 TAS regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029058 rbb4 retinoblastoma binding protein 4 protein_coding Danio_rerio
ENSMUSG00000057236 Rbbp4 retinoblastoma binding protein 4 protein_coding Mus_musculus

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