C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth factor independent 1 transcription repressor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162676 GFI1 9606 - 1:92474762-92486876 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000294702 GFI1-002 92474764-92486876 protein_coding
  ENST00000370332 GFI1-001 92474762-92483954 protein_coding
  ENST00000427103 GFI1-201 92474762-92486071 protein_coding
  ENST00000483490 GFI1-003 92482990-92484682 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000370332ENST00000427103
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000370332 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.721±0.00 N/A N/A N/A N/A
ENST00000427103 0.280±0.00 0.671±0.00 0.044±0.00 0.016±0.00 0.146±0.00 0.465±0.00 0.094±0.01 0.181±0.00 0.230±0.05 N/A 0.013±0.00 0.471±0.19 0.153±0.07 1.145±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ZO CIL_0005ZO_0001 CGP 1:92298965-92486876
CIL_0007C9 CIL_0007C9_0002 CGP 1:92474762-92792404

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000083 TAS regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007638 IEA mechanosensory behavior
GO:0008270 IEA zinc ion binding
GO:0009996 IEA negative regulation of cell fate specification
GO:0010956 IDA negative regulation of calcidiol 1-monooxygenase activity
GO:0010957 IC negative regulation of vitamin D biosynthetic process
GO:0010977 IDA negative regulation of neuron projection development
GO:0016032 TAS viral process
GO:0016363 IDA nuclear matrix
GO:0016604 IDA nuclear body
GO:0017053 IDA transcriptional repressor complex
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0034121 IDA regulation of toll-like receptor signaling pathway
GO:0042472 IEA inner ear morphogenesis
GO:0042491 IEA auditory receptor cell differentiation
GO:0042660 IEA positive regulation of cell fate specification
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045165 IEA cell fate commitment
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0070105 IDA positive regulation of interleukin-6-mediated signaling pathway
GO:0071222 IEP cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044457 gfi1ab growth factor independent 1ab protein_coding Danio_rerio
ENSMUSG00000029275 Gfi1 growth factor independent 1 protein_coding Mus_musculus

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