C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth factor independent 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029275 Gfi1 10090 - 5:107716657-107726036 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031205 Gfi1-002 107716657-107724343 protein_coding
  ENSMUST00000065478 Gfi1-201 107716666-107725805 protein_coding
  ENSMUST00000159164 Gfi1-001 107716657-107725805 protein_coding
  ENSMUST00000159263 Gfi1-003 107721606-107726036 protein_coding
  ENSMUST00000165344 Gfi1-202 107717224-107723961 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000031205ENSMUST00000065478ENSMUST00000159164ENSMUST00000159263ENSMUST00000165344
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000031205 0.060±0.03 0.134±0.00 0.064±0.00 N/A 0.538±0.46 2.737±1.68 N/A 0.076±0.02 0.403±0.22 0.317±0.13 N/A 0.370±0.18 0.108±0.04
ENSMUST00000065478 0.025±0.00 0.016±0.01 N/A 0.010±0.00 0.175±0.00 N/A 0.036±0.01 0.047±0.04 0.018±0.00 N/A 0.041±0.02 0.141±0.00 0.138±0.07
ENSMUST00000159164 0.024±0.00 0.016±0.01 N/A 0.008±0.00 0.151±0.00 N/A 0.032±0.01 0.028±0.01 0.441±0.33 N/A 0.024±0.02 N/A N/A
ENSMUST00000159263 N/A 0.132±0.04 N/A 0.021±0.00 1.227±0.00 N/A N/A 0.113±0.06 2.066±0.00 0.799±0.00 N/A 2.013±0.25 N/A
ENSMUST00000165344 0.133±0.08 0.030±0.00 0.067±0.01 0.055±0.00 0.203±0.10 1.509±0.00 0.039±0.02 0.085±0.02 0.340±0.25 0.162±0.13 0.051±0.00 0.408±0.00 0.353±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ZO CIL_0005ZO_0002 CGP 5:107597373-107726036
CIL_0007C9 CIL_0007C9_0003 CGP 5:107716657-107875107

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003676 IEA nucleic acid binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007638 IMP mechanosensory behavior
GO:0008270 IEA zinc ion binding
GO:0009996 IMP negative regulation of cell fate specification
GO:0010956 IEA negative regulation of calcidiol 1-monooxygenase activity
GO:0010977 ISS negative regulation of neuron projection development
GO:0016363 IEA nuclear matrix
GO:0016604 IEA nuclear body
GO:0017053 ISS transcriptional repressor complex
GO:0032088 IMP negative regulation of NF-kappaB transcription factor activity
GO:0034121 IEA regulation of toll-like receptor signaling pathway
GO:0042472 IMP inner ear morphogenesis
GO:0042491 IMP auditory receptor cell differentiation
GO:0042660 IMP positive regulation of cell fate specification
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045165 IMP cell fate commitment
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0070105 IEA positive regulation of interleukin-6-mediated signaling pathway
GO:0071222 IEP cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044457 gfi1ab growth factor independent 1ab protein_coding Danio_rerio
ENSG00000162676 GFI1 growth factor independent 1 transcription repressor protein_coding Homo_sapiens

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