C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calpain 2, (m/II) large subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162909 CAPN2 9606 + 1:223701593-223776018 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295006 CAPN2-001 223712332-223776018 protein_coding
  ENST00000433674 CAPN2-201 223701593-223776016 protein_coding
  ENST00000434648 CAPN2-009 223701645-223747063 protein_coding
  ENST00000463997 CAPN2-005 223770623-223776018 processed_transcript
  ENST00000472601 CAPN2-008 223769841-223772710 processed_transcript
  ENST00000474026 CAPN2-002 223757624-223776018 processed_transcript
  ENST00000480581 CAPN2-006 223752019-223757497 processed_transcript
  ENST00000483579 CAPN2-010 223747108-223749476 processed_transcript
  ENST00000487223 CAPN2-003 223758226-223776018 processed_transcript
  ENST00000492565 CAPN2-011 223759434-223764207 processed_transcript
  ENST00000492664 CAPN2-007 223770413-223772710 processed_transcript
  ENST00000498027 CAPN2-004 223770315-223773257 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295006ENST00000433674ENST00000474026ENST00000480581
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295006 102.339±0.00 57.311±0.00 10.202±0.00 14.442±10.67 43.551±23.43 33.580±14.35 16.540±12.62 100.807±0.00 9.231±0.59 41.842±26.00 30.233±26.26 45.773±27.45 41.319±9.72 25.585±17.95
ENST00000433674 N/A N/A N/A N/A N/A N/A N/A 2.700±0.00 N/A 5.590±0.00 N/A N/A 5.348±0.00 N/A
ENST00000474026 N/A N/A N/A N/A N/A N/A 0.985±0.00 N/A N/A 3.397±0.00 N/A N/A N/A N/A
ENST00000480581 N/A N/A 18.813±0.00 N/A N/A N/A N/A N/A N/A N/A 8.433±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000785 IEA chromatin
GO:0001666 IEA response to hypoxia
GO:0001824 IEA blastocyst development
GO:0004198 ISS:IEA calcium-dependent cysteine-type endopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006508 ISS:IEA proteolysis
GO:0007520 IEA myoblast fusion
GO:0008092 NAS cytoskeletal protein binding
GO:0008233 IEA peptidase activity
GO:0008234 TAS cysteine-type peptidase activity
GO:0016540 IEA protein autoprocessing
GO:0030425 ISS dendrite
GO:0030864 TAS cortical actin cytoskeleton
GO:0031143 IDA pseudopodium
GO:0045121 IDA membrane raft
GO:0046982 IEA protein heterodimerization activity
GO:0051493 TAS regulation of cytoskeleton organization
GO:0051603 IC proteolysis involved in cellular protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0071230 ISS cellular response to amino acid stimulus
GO:0097038 IDA perinuclear endoplasmic reticulum

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034211 capn2l calpain 2, (m/II) large subunit, like protein_coding Danio_rerio
ENSDARG00000055592 capn2b calpain 2, (m/II) large subunit b protein_coding Danio_rerio
ENSDARG00000090014 CAPN2 (3 of 4) calpain 2, (m/II) large subunit protein_coding Danio_rerio
ENSDARG00000091699 capn2a calpain 2, (m/II) large subunit a protein_coding Danio_rerio
ENSMUSG00000026509 Capn2 calpain 2 protein_coding Mus_musculus

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