C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuronal differentiation 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162992 NEUROD1 9606 - 2:181673088-181680876 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295108 NEUROD1-001 181676467-181680876 protein_coding
  ENST00000496876 NEUROD1-003 181673088-181680547 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonLiverMuscleTestisENST00000295108ENST00000496876
Transcript ID Brain Colon Liver Muscle Testis
ENST00000295108 1.000±0.49 0.205±0.00 0.050±0.00 0.038±0.00 0.582±0.00
ENST00000496876 0.983±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00080Y CIL_00080Y_0001 VISTA 2:181386314-181987082
CIL_0004C0 CIL_0004C0_0002 CGP 2:181457202-181680665
CIL_0004BX CIL_0004BX_0002 CGP 2:181536676-181680876
CIL_0004BY CIL_0004BY_0002 CGP 2:181673088-181930738

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0003326 IEA pancreatic A cell fate commitment
GO:0003329 IEA pancreatic PP cell fate commitment
GO:0003677 IEA DNA binding
GO:0003682 ISS chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IC nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006913 IEA nucleocytoplasmic transport
GO:0007263 IDA nitric oxide mediated signal transduction
GO:0008134 IPI transcription factor binding
GO:0009749 IMP response to glucose
GO:0009952 IEA anterior/posterior pattern specification
GO:0021542 ISS dentate gyrus development
GO:0021549 ISS cerebellum development
GO:0022008 TAS neurogenesis
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030073 IDA insulin secretion
GO:0030902 IEA hindbrain development
GO:0031018 ISS endocrine pancreas development
GO:0035881 ISS amacrine cell differentiation
GO:0035883 ISS enteroendocrine cell differentiation
GO:0042493 IEA response to drug
GO:0042593 ISS glucose homeostasis
GO:0043010 IEA camera-type eye development
GO:0043065 ISS positive regulation of apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0045165 IEA cell fate commitment
GO:0045597 ISS positive regulation of cell differentiation
GO:0045664 IEA regulation of neuron differentiation
GO:0045666 ISS positive regulation of neuron differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046426 IEA negative regulation of JAK-STAT cascade
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0048562 ISS embryonic organ morphogenesis
GO:0048839 ISS inner ear development
GO:0050796 IC regulation of insulin secretion
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060730 ISS regulation of intestinal epithelial structure maintenance
GO:0070888 IDA E-box binding
GO:0071156 ISS regulation of cell cycle arrest
GO:0071333 IEA cellular response to glucose stimulus
GO:2000675 ISS negative regulation of type B pancreatic cell apoptotic process
GO:2000679 IDA positive regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019566 neurod neurogenic differentiation protein_coding Danio_rerio
ENSMUSG00000034701 Neurod1 neurogenic differentiation 1 protein_coding Mus_musculus

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