C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inducible T-cell co-stimulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163600 ICOS 9606 + 2:203936748-203961577 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316386 ICOS-001 203936748-203961577 protein_coding
  ENST00000435193 ICOS-002 203936780-203961577 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000316386ENST00000435193
Transcript ID Adrenal Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000316386 0.929±0.00 0.214±0.11 N/A N/A N/A 0.247±0.00 0.470±0.12 0.089±0.06 0.032±0.00 N/A
ENST00000435193 0.169±0.00 N/A 0.044±0.00 0.035±0.00 0.091±0.00 0.017±0.00 N/A 0.079±0.04 0.018±0.00 0.115±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039C CIL_00039C_0001 CGP 2:203867786-203961577
CIL_0001R0 CIL_0001R0_0001 CGP 2:203936748-205620162

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002517 IEA T cell tolerance induction
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006955 NAS immune response
GO:0009897 IEA external side of plasma membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0031295 TAS T cell costimulation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026009 Icos inducible T cell co-stimulator protein_coding Mus_musculus

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