C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inducible T cell co-stimulator
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026009 Icos 10090 + 1:60977927-61000320 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027162 Icos-002 60977927-60995797 protein_coding
  ENSMUST00000102827 Icos-001 60977927-61000320 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027162ENSMUST00000102827
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027162 N/A N/A N/A 0.051±0.00 N/A 0.111±0.02 0.048±0.00 0.094±0.00 0.178±0.08 N/A N/A 0.139±0.10 0.087±0.00 0.024±0.00
ENSMUST00000102827 0.277±0.04 0.079±0.04 0.077±0.00 0.039±0.02 2.686±0.76 0.148±0.08 0.131±0.03 0.141±0.08 0.317±0.13 0.458±0.18 0.075±0.10 0.090±0.04 0.091±0.03 0.059±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039C CIL_00039C_0002 CGP 1:60887000-61000320
CIL_0001R0 CIL_0001R0_0002 CGP 1:60977927-62642284

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002517 IEA T cell tolerance induction
GO:0005515 IPI protein binding
GO:0005887 IDA integral component of plasma membrane
GO:0009897 IDA external side of plasma membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0031295 IEA T cell costimulation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000163600 ICOS inducible T-cell co-stimulator protein_coding Homo_sapiens

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