C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163739 CXCL1 9606 + 4:73869393-73871242 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000395761 CXCL1-001 73869404-73871242 protein_coding
  ENST00000509101 CXCL1-002 73869393-73870177 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000395761ENST00000509101
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000395761 0.922±0.00 1.457±0.00 0.866±0.43 1.363±1.00 1.242±0.38 0.314±0.27 3.232±0.00 1.652±0.17 17.854±15.55 0.117±0.00 19.837±15.11 2.428±1.74 0.182±0.15
ENST00000509101 N/A N/A N/A N/A N/A 0.521±0.00 0.383±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035Y CIL_00035Y_0001 CGP 4:73853189-73871242

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006935 TAS chemotaxis
GO:0006954 IEA inflammatory response
GO:0006955 IEA immune response
GO:0007165 TAS signal transduction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007399 TAS nervous system development
GO:0008009 IEA chemokine activity
GO:0008047 TAS enzyme activator activity
GO:0008083 IEA growth factor activity
GO:0008283 TAS cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0030036 TAS actin cytoskeleton organization
GO:0035556 TAS intracellular signal transduction
GO:0043085 TAS positive regulation of catalytic activity
GO:0060326 IEA cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000029379 Cxcl3 chemokine (C-X-C motif) ligand 3 protein_coding Mus_musculus
ENSMUSG00000029380 Cxcl1 chemokine (C-X-C motif) ligand 1 protein_coding Mus_musculus
ENSMUSG00000058427 Cxcl2 chemokine (C-X-C motif) ligand 2 protein_coding Mus_musculus

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