C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SUMO1/sentrin/SMT3 specific peptidase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163904 SENP2 9606 + 3:185582496-185633551 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296257 SENP2-001 185586174-185633551 protein_coding
  ENST00000413407 SENP2-002 185586295-185630405 nonsense_mediated_decay
  ENST00000430355 SENP2-004 185582496-185609285 protein_coding
  ENST00000439684 SENP2-007 185586295-185606491 nonsense_mediated_decay
  ENST00000444509 SENP2-012 185613355-185626307 protein_coding
  ENST00000453532 SENP2-006 185586241-185609318 nonsense_mediated_decay
  ENST00000458551 SENP2-008 185586298-185600825 nonsense_mediated_decay
  ENST00000459883 SENP2-010 185609003-185613374 retained_intron
  ENST00000465201 SENP2-005 185582784-185606490 processed_transcript
  ENST00000473760 SENP2-009 185598965-185613511 retained_intron
  ENST00000476011 SENP2-014 185612222-185613644 retained_intron
  ENST00000478001 SENP2-011 185611528-185617509 retained_intron
  ENST00000483005 SENP2-013 185614503-185619519 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296257ENST00000413407ENST00000439684ENST00000473760ENST00000478001
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296257 4.740±0.00 2.384±0.00 0.661±0.00 4.288±1.63 4.117±0.00 2.001±0.00 1.731±1.35 2.973±0.00 1.253±0.48 1.105±0.45 2.235±0.69 11.651±8.26 4.644±1.90 13.113±3.97
ENST00000413407 7.415±0.00 2.643±0.00 N/A 3.620±0.90 4.780±0.00 2.284±1.28 2.193±1.67 2.675±0.41 1.745±0.39 2.425±0.00 2.693±0.00 10.529±10.62 4.466±1.42 30.917±13.87
ENST00000439684 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.154±0.00 N/A N/A N/A
ENST00000473760 N/A N/A N/A 3.776±0.00 N/A N/A N/A N/A 3.214±0.00 N/A N/A N/A N/A N/A
ENST00000478001 N/A N/A 5.553±0.00 N/A 4.868±0.00 N/A N/A N/A 8.045±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZT CIL_0008ZT_0001 VISTA 3:185444884-186046681
CIL_0006RE CIL_0006RE_0001 CGP 3:185506262-185633551
CIL_0006RH CIL_0006RH_0001 CGP 3:185582496-185825056

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005643 IDA nuclear pore
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006508 IEA proteolysis
GO:0007507 IEA heart development
GO:0008234 IEA cysteine-type peptidase activity
GO:0009950 IEA dorsal/ventral axis specification
GO:0015031 IEA protein transport
GO:0016055 IEA Wnt signaling pathway
GO:0016604 IEA nuclear body
GO:0016605 ISS PML body
GO:0016925 TAS protein sumoylation
GO:0016926 IMP protein desumoylation
GO:0016929 IDA SUMO-specific protease activity
GO:0019904 IEA protein domain specific binding
GO:0030111 NAS regulation of Wnt signaling pathway
GO:0031410 IEA cytoplasmic vesicle
GO:0032091 IEA negative regulation of protein binding
GO:0032875 IEA regulation of DNA endoreduplication
GO:0035562 IEA negative regulation of chromatin binding
GO:0043518 IEA negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0051028 IEA mRNA transport
GO:0051246 IEA regulation of protein metabolic process
GO:0060707 IEA trophoblast giant cell differentiation
GO:0060711 IEA labyrinthine layer development
GO:0060712 IEA spongiotrophoblast layer development
GO:1901797 IEA negative regulation of signal transduction by p53 class mediator
GO:2000045 IEA regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073837 senp2 SUMO1/sentrin/SMT3 specific peptidase 2 protein_coding Danio_rerio
ENSMUSG00000022855 Senp2 SUMO/sentrin specific peptidase 2 protein_coding Mus_musculus

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