C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: E2F transcription factor 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000322886 E2F7-001 ENSG00000165891 9606 - 12:77021247-77065580 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainLungOvaryPlacentaTestisENST00000322886
Transcript ID Adipose Brain Lung Ovary Placenta Testis
ENST00000322886 0.019±0.00 0.050±0.00 0.011±0.00 0.306±0.13 0.152±0.05 0.815±0.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002BB CIL_0002BB_0002 CGP 12:76858715-77065580

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001890 ISS placenta development
GO:0002040 IMP sprouting angiogenesis
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003714 ISS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008285 IMP negative regulation of cell proliferation
GO:0030330 IDA DNA damage response, signal transduction by p53 class mediator
GO:0032466 ISS negative regulation of cytokinesis
GO:0032877 ISS positive regulation of DNA endoreduplication
GO:0042802 IPI identical protein binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0060707 ISS trophoblast giant cell differentiation
GO:0060718 ISS chorionic trophoblast cell differentiation
GO:0070365 ISS hepatocyte differentiation
GO:0071930 IDA negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:2000134 ISS negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000173471 E2f7-002 protein_coding Mus_musculus 0 2023
ENSMUST00000073781 E2f7-001 protein_coding Mus_musculus 0 2021
ENSMUST00000174810 E2f7-004 retained_intron Mus_musculus 0 1175
ENSMUST00000173948 E2f7-008 nonsense_mediated_decay Mus_musculus 0 782
ENSMUST00000174593 E2f7-009 retained_intron Mus_musculus 0 486
ENSDART00000007196 e2f7-201 protein_coding Danio_rerio 5e-23 115
ENSDART00000140760 e2f7-001 protein_coding Danio_rerio 5e-23 115

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