C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166501 PRKCB 9606 + 16:23836001-24220611 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000303531 PRKCB-002 23836024-24220611 protein_coding
  ENST00000321728 PRKCB-001 23836001-24220611 protein_coding
  ENST00000463752 PRKCB-008 24172176-24174930 retained_intron
  ENST00000466124 PRKCB-010 24185531-24191588 protein_coding
  ENST00000472066 PRKCB-007 24151685-24180845 protein_coding
  ENST00000482000 PRKCB-006 24092790-24111321 processed_transcript
  ENST00000486868 PRKCB-005 24031980-24092860 retained_intron
  ENST00000487674 PRKCB-009 24174216-24185567 retained_intron
  ENST00000498058 PRKCB-003 23836082-23869326 protein_coding
  ENST00000498739 PRKCB-004 23837223-24113065 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000303531ENST00000321728ENST00000482000ENST00000498739
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000303531 0.845±0.00 9.928±0.00 26.895±0.01 0.885±0.59 3.255±0.00 0.120±0.00 0.439±0.00 1.518±1.04 2.661±0.47 N/A 0.431±0.12 0.703±0.04 1.833±0.79
ENST00000321728 0.525±0.00 N/A 20.012±1.15 N/A N/A 0.376±0.00 N/A 0.328±0.00 2.977±0.53 0.083±0.01 0.372±0.03 0.742±0.13 2.985±0.00
ENST00000482000 N/A N/A N/A N/A N/A N/A 2.056±0.00 N/A N/A N/A N/A N/A N/A
ENST00000498739 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.782±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CY CIL_0006CY_0001 CGP 16:23754627-24220611
CIL_0003VA CIL_0003VA_0002 CGP 16:23836001-24362801

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IDA chromatin binding
GO:0004672 IEA protein kinase activity
GO:0004674 TAS:IEA protein serine/threonine kinase activity
GO:0004697 IEA protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005080 IPI protein kinase C binding
GO:0005246 IEA calcium channel regulator activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0006468 TAS:IEA protein phosphorylation
GO:0006816 IEA calcium ion transport
GO:0006874 IEA cellular calcium ion homeostasis
GO:0006915 IEA apoptotic process
GO:0007165 NAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0008270 IEA zinc ion binding
GO:0010829 ISS negative regulation of glucose transport
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030168 TAS platelet activation
GO:0030374 IMP ligand-dependent nuclear receptor transcription coactivator activity
GO:0030949 ISS positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0035403 IDA histone kinase activity (H3-T6 specific)
GO:0035408 IDA histone H3-T6 phosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0042113 ISS B cell activation
GO:0042393 IDA histone binding
GO:0042953 TAS lipoprotein transport
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045766 ISS positive regulation of angiogenesis
GO:0046627 ISS negative regulation of insulin receptor signaling pathway
GO:0050681 IDA androgen receptor binding
GO:0050853 ISS B cell receptor signaling pathway
GO:0050861 ISS positive regulation of B cell receptor signaling pathway
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0070062 IDA extracellular vesicular exosome
GO:0071322 IEA cellular response to carbohydrate stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008723 prkcba protein kinase C, beta a protein_coding Danio_rerio
ENSDARG00000022254 prkcbb protein kinase C, beta b protein_coding Danio_rerio
ENSMUSG00000052889 Prkcb protein kinase C, beta protein_coding Mus_musculus

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