C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: minichromosome maintenance complex component 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166508 MCM7 9606 - 7:100092728-100101940 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000303887 MCM7-001 100092781-100101940 protein_coding
  ENST00000343023 MCM7-003 100092780-100101940 protein_coding
  ENST00000354230 MCM7-201 100092729-100100780 protein_coding
  ENST00000425308 MCM7-009 100098140-100100869 protein_coding
  ENST00000463722 MCM7-007 100098059-100101409 retained_intron
  ENST00000465688 MCM7-015 100099464-100101310 retained_intron
  ENST00000465738 MCM7-011 100099686-100100393 retained_intron
  ENST00000467516 MCM7-016 100099319-100100473 retained_intron
  ENST00000477372 MCM7-010 100097613-100099345 retained_intron
  ENST00000485286 MCM7-006 100092781-100100757 retained_intron
  ENST00000489841 MCM7-002 100092728-100101370 retained_intron
  ENST00000491245 MCM7-005 100093292-100099737 nonsense_mediated_decay
  ENST00000493352 MCM7-014 100093316-100095664 retained_intron
  ENST00000621318 MCM7-202 100092729-100101940 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000303887ENST00000343023ENST00000425308ENST00000477372ENST00000485286ENST00000489841
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000303887 8.193±0.00 13.216±0.00 N/A N/A N/A N/A 3.518±3.03 11.585±0.00 3.913±0.00 7.385±0.00 26.847±0.00 24.909±20.61 15.317±2.81 36.970±0.18
ENST00000343023 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.954±0.00 9.103±0.00 N/A N/A
ENST00000425308 N/A N/A 1.782±0.00 N/A 6.129±0.00 N/A N/A 2.701±0.00 2.543±0.00 N/A N/A N/A N/A N/A
ENST00000477372 N/A N/A 3.316±0.00 N/A N/A N/A N/A 4.847±0.00 5.247±0.00 N/A N/A 75.142±53.51 38.022±0.00 93.019±0.00
ENST00000485286 N/A 10.261±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000489841 N/A 11.819±0.00 N/A 2.163±0.00 7.199±0.00 9.199±0.00 2.685±1.74 6.046±3.76 2.252±0.00 4.743±1.80 2.313±0.00 49.056±44.55 22.651±13.55 56.490±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QI CIL_0008QI_0001 VISTA 7:99696610-100298804
CIL_0003E2 CIL_0003E2_0001 CGP 7:100088954-100101940
CIL_0003DY CIL_0003DY_0001 CGP 7:100092728-100110345

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000785 TAS chromatin
GO:0003677 TAS:IEA DNA binding
GO:0003678 IEA DNA helicase activity
GO:0003697 IEA single-stranded DNA binding
GO:0004003 IDA ATP-dependent DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0006260 TAS:IEA DNA replication
GO:0006268 IEA DNA unwinding involved in DNA replication
GO:0006270 IEA DNA replication initiation
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0008283 IEA cell proliferation
GO:0015979 IEA photosynthesis
GO:0015995 IEA chlorophyll biosynthetic process
GO:0016020 IDA membrane
GO:0016851 IEA magnesium chelatase activity
GO:0016887 IEA ATPase activity
GO:0042325 IMP regulation of phosphorylation
GO:0042493 IEA response to drug
GO:0042555 IEA:IMP MCM complex
GO:0071310 IEA cellular response to organic substance
GO:0071364 IEA cellular response to epidermal growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035761 mcm7 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000029730 Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) protein_coding Mus_musculus

Loading