C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: beta-2-microglobulin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166710 B2M 9606 + 15:44711477-44718877 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000349264 B2M-007 44711517-44718067 nonsense_mediated_decay
  ENST00000544417 B2M-201 44711487-44718159 protein_coding
  ENST00000557901 B2M-003 44711519-44717622 nonsense_mediated_decay
  ENST00000558401 B2M-001 44711477-44718877 protein_coding
  ENST00000559220 B2M-012 44714507-44718144 processed_transcript
  ENST00000559720 B2M-002 44711487-44717765 nonsense_mediated_decay
  ENST00000559907 B2M-008 44711927-44717704 processed_transcript
  ENST00000559916 B2M-006 44711513-44717029 protein_coding
  ENST00000560556 B2M-010 44715726-44716939 processed_transcript
  ENST00000560681 B2M-009 44711959-44716559 retained_intron
  ENST00000561139 B2M-011 44715500-44718145 nonsense_mediated_decay
  ENST00000561424 B2M-013 44711509-44718851 nonsense_mediated_decay
  ENST00000623550 B2M-005 44715817-44718145 TEC

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000349264ENST00000544417ENST00000557901ENST00000559220ENST00000561139ENST00000561424
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000349264 402.493±0.00 654.770±0.00 N/A 95.886±0.00 292.787±0.00 344.475±0.00 330.623±0.00 470.359±0.00 416.278±0.00 1965.080±0.00 124.360±0.00 380.064±119.67 476.106±21.29 128.863±76.69
ENST00000544417 736.610±0.00 932.619±0.00 31.262±0.00 138.718±94.62 476.949±256.72 413.579±261.17 107.674±51.25 318.549±156.40 183.171±55.37 769.464±415.90 49.623±23.65 283.558±70.40 357.561±0.00 585.615±0.00
ENST00000557901 930.183±0.00 1177.300±0.00 N/A 214.697±0.00 881.740±0.00 600.540±0.00 432.658±0.00 609.782±0.00 582.348±0.00 3840.220±0.00 162.687±0.00 641.195±0.00 552.763±0.00 242.065±180.88
ENST00000559220 N/A N/A 130.614±0.00 213.314±0.00 733.994±0.00 649.898±0.00 142.438±0.00 668.755±0.00 385.319±0.00 977.542±0.00 115.116±0.00 645.450±107.25 860.827±439.22 N/A
ENST00000561139 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 362.689±0.00 388.036±0.00 35.326±0.00
ENST00000561424 N/A N/A 56.731±0.00 67.752±0.00 419.327±0.00 274.356±0.00 75.116±0.00 310.585±0.00 173.178±0.00 543.797±0.00 73.335±0.00 612.292±206.45 1105.340±105.06 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DK CIL_0004DK_0001 CGP 15:44665732-44718877
CIL_0004DL CIL_0004DL_0001 CGP 15:44711477-44767829

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0001895 IEP retina homeostasis
GO:0001916 IEA positive regulation of T cell mediated cytotoxicity
GO:0002237 IEA response to molecule of bacterial origin
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002480 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002481 IEA antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006955 NAS immune response
GO:0009897 IEA external side of plasma membrane
GO:0012507 TAS ER to Golgi transport vesicle membrane
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030670 TAS phagocytic vesicle membrane
GO:0031901 TAS early endosome membrane
GO:0031905 TAS early endosome lumen
GO:0033077 IEA T cell differentiation in thymus
GO:0042026 IEA protein refolding
GO:0042493 IEA response to drug
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042612 IEA MHC class I protein complex
GO:0042802 IPI identical protein binding
GO:0045087 TAS innate immune response
GO:0046686 IEA response to cadmium ion
GO:0050690 TAS regulation of defense response to virus by virus
GO:0050776 TAS regulation of immune response
GO:0055072 IEA iron ion homeostasis
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015887 b2ml beta-2-microglobulin, like protein_coding Danio_rerio
ENSDARG00000053136 b2m beta-2-microglobulin protein_coding Danio_rerio
ENSDARG00000071168 B2M (3 of 3) beta-2-microglobulin protein_coding Danio_rerio
ENSMUSG00000060802 B2m beta-2 microglobulin protein_coding Mus_musculus

Loading