C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: carbonic anhydrase IV
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167434 CA4 9606 + 17:60149936-60170899 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300900 CA4-001 60149936-60159540 protein_coding
  ENST00000585705 CA4-004 60149942-60156952 retained_intron
  ENST00000586876 CA4-002 60149942-60170899 nonsense_mediated_decay
  ENST00000587265 CA4-006 60158108-60158964 protein_coding
  ENST00000590203 CA4-005 60157732-60159546 protein_coding
  ENST00000591725 CA4-003 60149942-60157542 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300900ENST00000585705ENST00000586876ENST00000587265ENST00000590203
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300900 162.610±0.00 4.455±0.00 N/A 3.731±1.63 18.973±18.40 19.381±0.00 6.679±5.44 20.418±0.00 0.369±0.00 23.033±20.47 1.363±0.00 2.231±1.95 8.265±5.46 1.869±1.48
ENST00000585705 N/A N/A 1.117±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000586876 N/A N/A N/A N/A N/A N/A N/A N/A 0.035±0.00 N/A N/A N/A N/A N/A
ENST00000587265 N/A N/A N/A N/A N/A N/A 0.423±0.00 N/A 0.088±0.00 N/A N/A 0.079±0.00 N/A N/A
ENST00000590203 37.850±0.00 1.621±0.00 N/A 1.412±0.45 12.109±0.00 N/A N/A N/A N/A 6.590±5.52 1.119±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008VS CIL_0008VS_0001 VISTA 17:59556856-60159441
CIL_0006V1 CIL_0006V1_0001 CGP 17:60149936-60422470

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004089 TAS carbonate dehydratase activity
GO:0005515 IPI protein binding
GO:0005791 IDA rough endoplasmic reticulum
GO:0005793 IDA endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 IDA Golgi apparatus
GO:0005802 IDA trans-Golgi network
GO:0005886 IDA plasma membrane
GO:0006730 IEA one-carbon metabolic process
GO:0008152 IEA metabolic process
GO:0008270 IEA zinc ion binding
GO:0009986 IDA cell surface
GO:0015701 IMP bicarbonate transport
GO:0016020 TAS membrane
GO:0016324 IDA apical plasma membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0030658 IDA transport vesicle membrane
GO:0030667 IDA secretory granule membrane
GO:0031225 IEA anchored component of membrane
GO:0031362 IDA anchored component of external side of plasma membrane
GO:0031526 IDA brush border membrane
GO:0042383 IEA sarcolemma
GO:0042493 IEA response to drug
GO:0044281 TAS small molecule metabolic process
GO:0046658 IEA anchored component of plasma membrane
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048513 IEA organ development
GO:0048545 IEA response to steroid hormone
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002259 ca15c carbonic anhydrase XV c protein_coding Danio_rerio
ENSDARG00000015654 ca15a carbonic anhydrase XV a protein_coding Danio_rerio
ENSDARG00000040510 ca15b carbonic anhydrase XV b protein_coding Danio_rerio
ENSDARG00000074666 CA4 (4 of 5) carbonic anhydrase IV protein_coding Danio_rerio
ENSDARG00000087756 CA4 (5 of 5) carbonic anhydrase IV protein_coding Danio_rerio
ENSMUSG00000000805 Car4 carbonic anhydrase 4 protein_coding Mus_musculus

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