C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SMG8 nonsense mediated mRNA decay factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167447 SMG8 9606 + 17:59209400-59215247 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300917 SMG8-201 59210010-59215247 protein_coding
  ENST00000543872 SMG8-001 59209400-59215239 protein_coding
  ENST00000578922 SMG8-002 59209867-59212044 protein_coding
  ENST00000580498 SMG8-005 59210022-59213127 processed_transcript
  ENST00000580798 SMG8-004 59211722-59212856 nonsense_mediated_decay
  ENST00000582469 SMG8-003 59211423-59215200 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300917ENST00000543872ENST00000578922ENST00000580498ENST00000582469
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300917 1.784±0.00 3.645±0.00 0.249±0.00 2.821±0.92 1.790±0.15 1.727±0.05 1.873±0.51 1.801±1.32 1.716±0.68 1.056±0.56 1.933±0.00 3.910±0.67 4.956±0.42 5.294±0.90
ENST00000543872 N/A N/A N/A 0.545±0.00 1.359±0.00 N/A N/A N/A 0.529±0.00 0.328±0.00 N/A N/A N/A N/A
ENST00000578922 N/A N/A 1.007±0.00 N/A N/A N/A N/A N/A N/A N/A 0.450±0.00 N/A N/A N/A
ENST00000580498 N/A N/A 1.594±0.00 N/A N/A N/A N/A 1.313±0.00 N/A N/A 0.271±0.00 N/A N/A N/A
ENST00000582469 N/A N/A N/A N/A N/A N/A N/A N/A 0.901±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 IMP:IEA nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0005515 IPI protein binding
GO:0005575 ND cellular_component
GO:0005829 TAS cytosol
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0045859 IMP regulation of protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061378 smg8 smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) protein_coding Danio_rerio
ENSMUSG00000020495 Smg8 smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) protein_coding Mus_musculus

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