C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168394 TAP1 9606 - 6:32845209-32853978 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354258 TAP1-001 32845209-32853978 protein_coding
  ENST00000486332 TAP1-002 32845209-32850142 retained_intron
  ENST00000487296 TAP1-003 32845675-32848230 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354258ENST00000487296
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354258 24.320±0.00 35.274±0.00 1.219±0.00 5.905±3.74 15.058±2.79 14.275±1.16 7.204±5.15 11.303±7.75 6.928±2.12 109.679±0.00 11.342±0.00 27.699±20.07 27.160±4.56 10.554±5.94
ENST00000487296 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.175±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000423 CIL_000423_0001 CGP 6:32844136-32859585

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 IEA transport
GO:0006952 IEA defense response
GO:0015197 IMP peptide transporter activity
GO:0015440 IEA peptide-transporting ATPase activity
GO:0015833 IMP peptide transport
GO:0016020 IDA membrane
GO:0016021 IDA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0019060 IMP intracellular transport of viral protein in host cell
GO:0019885 IMP:IEA antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 IPI MHC class Ib protein binding
GO:0030176 IDA:IEA integral component of endoplasmic reticulum membrane
GO:0042287 IEA MHC protein binding
GO:0042288 IEA MHC class I protein binding
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 NAS peptide antigen binding
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0042803 ISS protein homodimerization activity
GO:0042825 IDA:IEA TAP complex
GO:0043531 IDA ADP binding
GO:0046967 IMP cytosol to ER transport
GO:0046978 ISS TAP1 binding
GO:0046979 IPI TAP2 binding
GO:0055085 IBA:IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079766 tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) protein_coding Danio_rerio
ENSMUSG00000037321 Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) protein_coding Mus_musculus

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