C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000354258 TAP1-001 ENSG00000168394 9606 - 6:32845209-32853978 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354258
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354258 24.320±0.00 35.274±0.00 1.219±0.00 5.905±3.74 15.058±2.79 14.275±1.16 7.204±5.15 11.303±7.75 6.928±2.12 109.679±0.00 11.342±0.00 27.699±20.07 27.160±4.56 10.554±5.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000423 CIL_000423_0001 CGP 6:32844136-32859585

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 IEA transport
GO:0006952 IEA defense response
GO:0015197 IMP peptide transporter activity
GO:0015440 IEA peptide-transporting ATPase activity
GO:0015833 IMP peptide transport
GO:0016020 IDA membrane
GO:0016021 IDA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0019060 IMP intracellular transport of viral protein in host cell
GO:0019885 IMP:IEA antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 IPI MHC class Ib protein binding
GO:0030176 IDA:IEA integral component of endoplasmic reticulum membrane
GO:0042287 IEA MHC protein binding
GO:0042288 IEA MHC class I protein binding
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 NAS peptide antigen binding
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0042803 ISS protein homodimerization activity
GO:0042825 IDA:IEA TAP complex
GO:0043531 IDA ADP binding
GO:0046967 IMP cytosol to ER transport
GO:0046978 ISS TAP1 binding
GO:0046979 IPI TAP2 binding
GO:0055085 IBA:IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000170086 Tap1-001 protein_coding Mus_musculus 0 1482
ENSMUST00000166853 Tap1-003 retained_intron Mus_musculus 0 1147
ENSMUST00000168351 Tap1-004 retained_intron Mus_musculus 0 1027
ENSMUST00000041633 Tap1-005 protein_coding Mus_musculus 0 778
ENSMUST00000166582 Tap1-006 retained_intron Mus_musculus 0 645
ENSMUST00000171148 Tap1-007 protein_coding Mus_musculus 0 233

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