C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168495 POLR3D 9606 + 8:22245104-22254600 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306433 POLR3D-003 22245104-22251167 protein_coding
  ENST00000397802 POLR3D-001 22245235-22254600 protein_coding
  ENST00000517789 POLR3D-006 22247221-22250159 retained_intron
  ENST00000518039 POLR3D-002 22245432-22250896 nonsense_mediated_decay
  ENST00000519237 POLR3D-005 22245166-22248617 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306433ENST00000397802ENST00000517789ENST00000518039ENST00000519237
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306433 5.091±0.00 3.595±0.00 1.296±0.00 1.896±0.33 2.316±0.83 4.871±2.62 2.416±0.84 5.464±0.00 2.099±0.01 6.291±3.90 13.760±0.00 4.834±3.00 7.799±2.42 11.550±7.55
ENST00000397802 0.720±0.00 N/A N/A 0.844±0.11 0.612±0.00 0.482±0.07 0.503±0.00 0.447±0.04 0.959±0.00 1.149±0.00 0.652±0.33 0.807±0.11 0.784±0.28 2.036±0.24
ENST00000517789 N/A N/A N/A 1.373±0.00 1.826±0.00 2.597±1.36 N/A 0.465±0.00 1.400±0.00 2.223±0.00 1.937±0.00 4.311±0.00 N/A N/A
ENST00000518039 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.269±0.00 1.369±0.00 1.805±0.00 5.151±0.00
ENST00000519237 N/A N/A N/A N/A N/A N/A N/A 1.948±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000810 CIL_000810_0001 VISTA 8:21687877-22288944
CIL_0008ZI CIL_0008ZI_0001 VISTA 8:21743578-22344815
CIL_000812 CIL_000812_0001 VISTA 8:21749915-22350771

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0001056 IBA RNA polymerase III activity
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003899 IEA DNA-directed RNA polymerase activity
GO:0005654 TAS nucleoplasm
GO:0005666 IEA:IBA DNA-directed RNA polymerase III complex
GO:0005829 TAS cytosol
GO:0006383 IEA:TAS transcription from RNA polymerase III promoter
GO:0006385 TAS transcription elongation from RNA polymerase III promoter
GO:0006386 TAS termination of RNA polymerase III transcription
GO:0010467 TAS gene expression
GO:0032481 TAS positive regulation of type I interferon production
GO:0032728 IDA positive regulation of interferon-beta production
GO:0045087 TAS innate immune response
GO:0045089 IDA positive regulation of innate immune response
GO:0051607 IEA defense response to virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017820 polr3d polymerase (RNA) III (DNA directed) polypeptide D protein_coding Danio_rerio
ENSMUSG00000000776 Polr3d polymerase (RNA) III (DNA directed) polypeptide D protein_coding Mus_musculus

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