C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TNFAIP3 interacting protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168884 TNIP2 9606 - 4:2741648-2756376 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315423 TNIP2-001 2741660-2756376 protein_coding
  ENST00000502256 TNIP2-007 2742075-2744863 retained_intron
  ENST00000503235 TNIP2-003 2741698-2756342 protein_coding
  ENST00000505186 TNIP2-006 2742130-2746158 processed_transcript
  ENST00000507686 TNIP2-005 2745336-2756024 retained_intron
  ENST00000510267 TNIP2-002 2741648-2756331 protein_coding
  ENST00000511352 TNIP2-004 2747450-2756024 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000315423ENST00000502256ENST00000503235ENST00000505186
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000315423 21.689±0.00 28.154±0.00 0.800±0.00 2.179±1.40 9.668±6.77 12.412±9.01 6.012±4.80 15.157±13.40 5.780±3.90 17.057±14.28 11.819±9.09 16.478±7.80 21.367±4.17 22.764±5.65
ENST00000502256 N/A 12.069±0.00 N/A 1.389±0.00 N/A 5.424±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000503235 N/A N/A N/A 0.186±0.00 N/A 0.771±0.00 N/A N/A N/A N/A N/A 1.071±0.00 3.413±0.00 3.788±0.00
ENST00000505186 N/A N/A N/A N/A N/A N/A 0.923±0.00 0.850±0.00 0.778±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OC CIL_0003OC_0002 CGP 4:2625261-2756376
CIL_0003SI CIL_0003SI_0001 CGP 4:2741648-2841098

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0006954 IEA inflammatory response
GO:0007249 IEA I-kappaB kinase/NF-kappaB signaling
GO:0019901 IDA protein kinase binding
GO:0023035 ISS CD40 signaling pathway
GO:0031593 IDA polyubiquitin binding
GO:0034134 ISS toll-like receptor 2 signaling pathway
GO:0034138 ISS toll-like receptor 3 signaling pathway
GO:0034162 ISS toll-like receptor 9 signaling pathway
GO:0043032 ISS positive regulation of macrophage activation
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050821 ISS protein stabilization
GO:0050871 ISS positive regulation of B cell activation
GO:0070498 ISS interleukin-1-mediated signaling pathway
GO:0071222 ISS cellular response to lipopolysaccharide
GO:2000352 IDA negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074501 TNIP2 TNFAIP3 interacting protein 2 protein_coding Danio_rerio
ENSMUSG00000059866 Tnip2 TNFAIP3 interacting protein 2 protein_coding Mus_musculus

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