C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TNFAIP3 interacting protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059866 Tnip2 10090 - 5:34496087-34513997 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030991 Tnip2-002 34496087-34513963 protein_coding
  ENSMUST00000087737 Tnip2-001 34496087-34513991 protein_coding
  ENSMUST00000114359 Tnip2-003 34496130-34513938 protein_coding
  ENSMUST00000137555 Tnip2-004 34501172-34513849 retained_intron
  ENSMUST00000143072 Tnip2-005 34499605-34501618 retained_intron
  ENSMUST00000144791 Tnip2-006 34496089-34513997 retained_intron
  ENSMUST00000159102 Tnip2-007 34503286-34513660 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030991ENSMUST00000087737ENSMUST00000114359ENSMUST00000137555ENSMUST00000144791
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030991 N/A N/A N/A N/A N/A N/A N/A 0.809±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000087737 4.768±1.58 N/A 8.082±0.39 4.079±3.17 7.862±5.38 7.541±4.17 3.071±0.85 3.818±0.70 2.647±1.15 7.788±2.69 1.039±0.20 14.414±6.72 4.392±1.61 2.109±0.95
ENSMUST00000114359 2.790±0.00 25.124±8.36 N/A N/A 6.701±0.00 6.245±2.46 1.164±0.00 N/A 2.738±1.22 3.598±0.00 N/A 15.421±4.88 N/A N/A
ENSMUST00000137555 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.806±0.00 N/A N/A N/A
ENSMUST00000144791 1.896±0.00 6.424±0.00 3.848±0.00 2.060±1.28 N/A 2.565±0.00 1.102±0.00 N/A 0.835±0.16 N/A 0.523±0.01 3.956±0.00 N/A 0.841±0.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OC CIL_0003OC_0003 CGP 5:34369933-34513997
CIL_0003SI CIL_0003SI_0002 CGP 5:34496087-34563638

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0006954 IEA inflammatory response
GO:0007249 IDA I-kappaB kinase/NF-kappaB signaling
GO:0019901 ISS protein kinase binding
GO:0023035 IMP CD40 signaling pathway
GO:0031593 IEA polyubiquitin binding
GO:0034134 IMP toll-like receptor 2 signaling pathway
GO:0034138 IMP toll-like receptor 3 signaling pathway
GO:0034162 IMP toll-like receptor 9 signaling pathway
GO:0043032 IMP positive regulation of macrophage activation
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0050821 IMP protein stabilization
GO:0050871 IMP positive regulation of B cell activation
GO:0070498 IMP interleukin-1-mediated signaling pathway
GO:0071222 IMP cellular response to lipopolysaccharide
GO:2000352 ISS negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074501 TNIP2 TNFAIP3 interacting protein 2 protein_coding Danio_rerio
ENSG00000168884 TNIP2 TNFAIP3 interacting protein 2 protein_coding Homo_sapiens

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