C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: TNFAIP3 interacting protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000315423 TNIP2-001 ENSG00000168884 9606 - 4:2741660-2756376 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000315423
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000315423 21.689±0.00 28.154±0.00 0.800±0.00 2.179±1.40 9.668±6.77 12.412±9.01 6.012±4.80 15.157±13.40 5.780±3.90 17.057±14.28 11.819±9.09 16.478±7.80 21.367±4.17 22.764±5.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OC CIL_0003OC_0002 CGP 4:2625261-2756376
CIL_0003SI CIL_0003SI_0001 CGP 4:2741648-2841098

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0006954 IEA inflammatory response
GO:0007249 IEA I-kappaB kinase/NF-kappaB signaling
GO:0019901 IDA protein kinase binding
GO:0023035 ISS CD40 signaling pathway
GO:0031593 IDA polyubiquitin binding
GO:0034134 ISS toll-like receptor 2 signaling pathway
GO:0034138 ISS toll-like receptor 3 signaling pathway
GO:0034162 ISS toll-like receptor 9 signaling pathway
GO:0043032 ISS positive regulation of macrophage activation
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050821 ISS protein stabilization
GO:0050871 ISS positive regulation of B cell activation
GO:0070498 ISS interleukin-1-mediated signaling pathway
GO:0071222 ISS cellular response to lipopolysaccharide
GO:2000352 IDA negative regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000087737 Tnip2-001 protein_coding Mus_musculus 0 1007
ENSMUST00000144791 Tnip2-006 retained_intron Mus_musculus 0 704
ENSMUST00000030991 Tnip2-002 protein_coding Mus_musculus 0 617
ENSMUST00000114359 Tnip2-003 protein_coding Mus_musculus 0 492
ENSMUST00000143072 Tnip2-005 retained_intron Mus_musculus 0 209

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