C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase A2, group IVF
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168907 PLA2G4F 9606 - 15:42139034-42156636 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290497 PLA2G4F-003 42141204-42156611 nonsense_mediated_decay
  ENST00000397272 PLA2G4F-001 42139034-42156636 protein_coding
  ENST00000561627 PLA2G4F-007 42150665-42156609 nonsense_mediated_decay
  ENST00000561893 PLA2G4F-008 42146675-42147733 retained_intron
  ENST00000562320 PLA2G4F-005 42141198-42145587 nonsense_mediated_decay
  ENST00000565553 PLA2G4F-006 42154122-42156636 nonsense_mediated_decay
  ENST00000569985 PLA2G4F-002 42141209-42156618 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290497ENST00000397272ENST00000561627ENST00000561893ENST00000562320ENST00000569985
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290497 0.029±0.00 N/A 0.514±0.00 0.005±0.00 N/A 0.025±0.00 1.296±0.00 0.026±0.00 1.077±0.00 2.707±0.00 2.895±2.30 0.088±0.04 N/A
ENST00000397272 N/A 0.022±0.00 N/A 0.017±0.00 N/A 0.150±0.12 1.408±0.00 0.021±0.00 N/A N/A 1.304±0.00 N/A N/A
ENST00000561627 0.044±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000561893 N/A N/A N/A N/A N/A N/A N/A 0.168±0.00 N/A N/A N/A 0.108±0.00 N/A
ENST00000562320 0.012±0.00 N/A N/A N/A 0.991±0.45 0.378±0.00 N/A 0.202±0.00 0.801±0.00 N/A 2.899±2.89 0.168±0.13 0.071±0.00
ENST00000569985 0.005±0.00 N/A N/A 0.005±0.00 N/A 1.327±0.00 2.835±0.00 N/A 0.813±0.00 0.912±0.00 0.869±0.00 N/A 0.205±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005PO CIL_0005PO_0001 CGP 15:42067009-42156636
CIL_0005PN CIL_0005PN_0001 CGP 15:42139034-42208316

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001516 IEA prostaglandin biosynthetic process
GO:0004620 IEA phospholipase activity
GO:0004622 IEA lysophospholipase activity
GO:0004623 IEA phospholipase A2 activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005764 IEA lysosome
GO:0005829 TAS cytosol
GO:0006644 TAS phospholipid metabolic process
GO:0008152 IEA metabolic process
GO:0009395 IEA phospholipid catabolic process
GO:0015908 IEA fatty acid transport
GO:0031982 IEA vesicle
GO:0032587 IEA ruffle membrane
GO:0036148 TAS phosphatidylglycerol acyl-chain remodeling
GO:0036149 TAS phosphatidylinositol acyl-chain remodeling
GO:0036150 TAS phosphatidylserine acyl-chain remodeling
GO:0036151 TAS phosphatidylcholine acyl-chain remodeling
GO:0036152 TAS phosphatidylethanolamine acyl-chain remodeling
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0046872 IEA metal ion binding
GO:0047498 IEA calcium-dependent phospholipase A2 activity
GO:0050482 IEA arachidonic acid secretion
GO:0071236 IEA cellular response to antibiotic
GO:0071407 IEA cellular response to organic cyclic compound

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056535 PLA2G4F (1 of 2) phospholipase A2, group IVF protein_coding Danio_rerio
ENSDARG00000070953 PLA2G4F (2 of 2) phospholipase A2, group IVF protein_coding Danio_rerio
ENSMUSG00000046971 Pla2g4f phospholipase A2, group IVF protein_coding Mus_musculus

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