C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: receptor tyrosine kinase-like orphan receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169071 ROR2 9606 - 9:91563091-91950162 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375708 ROR2-001 91722597-91950162 protein_coding
  ENST00000375715 ROR2-002 91563091-91948880 protein_coding
  ENST00000476440 ROR2-005 91923653-91949906 processed_transcript
  ENST00000493846 ROR2-004 91923668-91948715 processed_transcript
  ENST00000495386 ROR2-003 91757334-91948676 processed_transcript
  ENST00000546883 ROR2-007 91757436-91948741 processed_transcript
  ENST00000548585 ROR2-008 91755940-91775781 retained_intron
  ENST00000550066 ROR2-006 91722602-91887199 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375708ENST00000375715ENST00000495386ENST00000550066
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375708 0.587±0.00 0.753±0.00 0.105±0.00 0.158±0.12 1.077±0.13 8.027±7.71 0.122±0.09 1.141±0.00 2.647±0.00 2.306±1.77 0.047±0.03 9.765±5.76 4.112±0.58 6.389±3.02
ENST00000375715 0.112±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000495386 N/A N/A N/A 0.183±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000550066 N/A N/A N/A 0.041±0.00 N/A N/A N/A 0.156±0.00 0.077±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00068R CIL_00068R_0001 CGP 9:91409045-91950162
CIL_0002JG CIL_0002JG_0001 CGP 9:91563091-92115384

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IEA skeletal system development
GO:0001502 IEA cartilage condensation
GO:0001756 IEA somitogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005109 IEA frizzled binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007223 IEA Wnt signaling pathway, calcium modulating pathway
GO:0007254 IEA JNK cascade
GO:0007275 TAS multicellular organismal development
GO:0008285 IMP negative regulation of cell proliferation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017147 IPI Wnt-protein binding
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030154 IEA cell differentiation
GO:0030335 IDA positive regulation of cell migration
GO:0030538 IEA embryonic genitalia morphogenesis
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042472 IEA inner ear morphogenesis
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0060071 IEA Wnt signaling pathway, planar cell polarity pathway
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:0090263 IEA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076227 ror2 receptor tyrosine kinase-like orphan receptor 2 protein_coding Danio_rerio
ENSMUSG00000021464 Ror2 receptor tyrosine kinase-like orphan receptor 2 protein_coding Mus_musculus

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