C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SIN3 transcription regulator family member A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169375 SIN3A 9606 - 15:75369379-75455842 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360439 SIN3A-002 75370933-75455783 protein_coding
  ENST00000394947 SIN3A-001 75369379-75451704 protein_coding
  ENST00000394949 SIN3A-004 75371130-75451585 protein_coding
  ENST00000562776 SIN3A-007 75414252-75455026 protein_coding
  ENST00000564778 SIN3A-005 75412990-75455842 protein_coding
  ENST00000565264 SIN3A-008 75430321-75451746 protein_coding
  ENST00000566640 SIN3A-010 75371982-75376380 retained_intron
  ENST00000567289 SIN3A-003 75419210-75451664 protein_coding
  ENST00000568190 SIN3A-013 75422719-75455815 protein_coding
  ENST00000568309 SIN3A-015 75422692-75455815 protein_coding
  ENST00000568431 SIN3A-014 75414287-75455813 protein_coding
  ENST00000568919 SIN3A-012 75430069-75451537 retained_intron
  ENST00000570021 SIN3A-009 75384008-75389821 retained_intron
  ENST00000570115 SIN3A-006 75422643-75455840 protein_coding
  ENST00000570124 SIN3A-011 75375740-75381088 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360439ENST00000394947ENST00000394949
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360439 N/A N/A 1.826±0.00 2.234±0.00 2.270±0.00 3.252±0.12 N/A 2.710±0.00 3.017±0.00 9.704±0.00 3.546±2.12 8.587±3.35 7.127±1.80 9.636±1.93
ENST00000394947 5.049±0.00 N/A 0.966±0.00 2.786±1.80 2.894±1.55 1.965±0.00 1.542±0.77 3.103±0.00 N/A N/A N/A 4.203±1.79 3.259±0.55 8.012±0.00
ENST00000394949 10.410±0.00 18.156±0.00 1.275±0.00 7.661±0.00 4.556±2.25 4.811±2.47 3.280±1.69 5.113±2.50 2.165±0.46 7.339±0.00 4.083±0.00 5.729±3.19 9.018±0.00 17.615±0.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000F8 CIL_0000F8_0002 CGP 15:75369379-75579289

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000776 IEA kinetochore
GO:0000785 IEA chromatin
GO:0000976 ISS transcription regulatory region sequence-specific DNA binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001103 IEA RNA polymerase II repressing transcription factor binding
GO:0001106 IEA RNA polymerase II transcription corepressor activity
GO:0001701 IEA in utero embryonic development
GO:0002218 IMP activation of innate immune response
GO:0002230 IMP positive regulation of defense response to virus by host
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 ISS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006260 IEA DNA replication
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006476 IMP protein deacetylation
GO:0007568 IEA aging
GO:0007596 TAS blood coagulation
GO:0008134 IEA transcription factor binding
GO:0010243 IEA response to organonitrogen compound
GO:0010971 IEA positive regulation of G2/M transition of mitotic cell cycle
GO:0016580 IDA Sin3 complex
GO:0017053 IEA transcriptional repressor complex
GO:0031937 IMP positive regulation of chromatin silencing
GO:0032403 IEA protein complex binding
GO:0033558 IMP protein deacetylase activity
GO:0034613 IEA cellular protein localization
GO:0042754 ISS negative regulation of circadian rhythm
GO:0043066 IEA negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0043619 IEA regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045171 IDA intercellular bridge
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048511 IEA rhythmic process
GO:0051595 IEA response to methylglyoxal
GO:0071333 IEA cellular response to glucose stimulus
GO:1900181 IMP negative regulation of protein localization to nucleus
GO:1901675 IMP negative regulation of histone H3-K27 acetylation
GO:2000678 IMP negative regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059812 sin3ab SIN3 homolog A, transcription regulator (yeast) b protein_coding Danio_rerio
ENSDARG00000079716 sin3aa SIN3 homolog A, transcription regulator (yeast) a protein_coding Danio_rerio
ENSMUSG00000042557 Sin3a transcriptional regulator, SIN3A (yeast) protein_coding Mus_musculus

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